Technology Process of 7-chloro-6-(4-nitrophenyl)quinoline-5,8-dione
There total 7 articles about 7-chloro-6-(4-nitrophenyl)quinoline-5,8-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; sodium hydrogencarbonate; triphenylphosphine;
In
N,N-dimethyl-formamide;
at 180 ℃;
for 3h;
DOI:10.1002/jhet.2745
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hypochlorite / acetic acid / 3.5 h / 20 °C
2: sodium dithionite; sulfuric acid / Inert atmosphere
3: potassium dichromate / Acidic conditions
4: palladium diacetate; triphenylphosphine; sodium hydrogencarbonate / N,N-dimethyl-formamide / 3 h / 180 °C
With
potassium dichromate; sodium hypochlorite; sodium dithionite; sulfuric acid; palladium diacetate; sodium hydrogencarbonate; triphenylphosphine;
In
acetic acid; N,N-dimethyl-formamide;
4: |Heck Reaction;
DOI:10.1002/jhet.2745
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium dithionite; sulfuric acid / Inert atmosphere
2: potassium dichromate / Acidic conditions
3: palladium diacetate; triphenylphosphine; sodium hydrogencarbonate / N,N-dimethyl-formamide / 3 h / 180 °C
With
potassium dichromate; sodium dithionite; sulfuric acid; palladium diacetate; sodium hydrogencarbonate; triphenylphosphine;
In
N,N-dimethyl-formamide;
3: |Heck Reaction;
DOI:10.1002/jhet.2745
