1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester

Base Information

• Chemical Name: 1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester
• CAS No.: 83181-07-1
• Molecular Formula: C₁₉H₂₆O₂S
• Molecular Weight: 318.48
• Mol file: 83181-07-1.mol

Synonyms:1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester

Chemical Property of 1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester

There total 2 articles about 1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1-methoxy-1-trimethylsilyloxymethylenecyclohexane (40195-26-4) + 1-chloro-3-methylbut-3-en-1-yl phenyl sulfide (80352-67-6) → 1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester (83181-07-1)

Guidance literature:

zinc dibromide; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(00)87352-9

Reference yield:

(3-methylbut-3-en-1-yl)(phenyl)sulfane (72445-18-2) → 1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester (83181-07-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / NCS / CCl₄ / 14 h / 20 °C

2: 74 percent / ZnBr₂ / CH₂Cl₂ / Ambient temperature

With N-chloro-succinimide; zinc dibromide; In tetrachloromethane; dichloromethane;

DOI:10.1016/S0040-4039(00)87352-9

Reference yield:

1-(3-Methyl-1-phenylsulfanyl-but-3-enyl)-cyclohexanecarboxylic acid methyl ester (83181-07-1) → 1-((E)-3-Oxo-but-1-enyl)-cyclohexanecarboxylic acid ethyl ester

Guidance literature:

With dimethylsulfide; ozone; Yield given. Multistep reaction; 1.) CH₂Cl₂, MeOH, -78 deg C 2.) -78 to 25 deg C, CCl₄, reflux;

DOI:10.1016/S0040-4039(00)87352-9

upstream raw materials:

1-methoxy-1-trimethylsilyloxymethylenecyclohexane

1-chloro-3-methylbut-3-en-1-yl phenyl sulfide

(3-methylbut-3-en-1-yl)(phenyl)sulfane