1-[¹³C]-2',4',6'-trihydroxyacetophenone

Base Information

• Chemical Name: 1-[¹³C]-2',4',6'-trihydroxyacetophenone
• CAS No.: 1256496-52-2
• Molecular Formula: C₈H₈O₄
• Molecular Weight: 169.138

Synonyms:1-[¹³C]-2',4',6'-trihydroxyacetophenone

Chemical Property of 1-[¹³C]-2',4',6'-trihydroxyacetophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[¹³C]-2',4',6'-trihydroxyacetophenone

There total 2 articles about 1-[¹³C]-2',4',6'-trihydroxyacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

3,5-dihydroxyphenol (108-73-6) + [1-13C]acetyl chloride (1520-57-6) → 1-[13C]-2',4',6'-trihydroxyacetophenone (1256496-52-2)

Guidance literature:

3,5-dihydroxyphenol; With aluminum (III) chloride; In nitromethane; dichloromethane; at 20 ℃; for 0.5h; Inert atmosphere;

[1-13C]acetyl chloride; In nitromethane; dichloromethane; for 3h; Inert atmosphere; Reflux;

DOI:10.1002/jlcr.3571

Reference yield: 39.0%

3,5-dihydroxyphenol (108-73-6) + 1-[13C]acetonitrile (31432-55-0) → 1-[13C]-2',4',6'-trihydroxyacetophenone (1256496-52-2)

Guidance literature:

3,5-dihydroxyphenol; With zinc(II) chloride; In diethyl ether; at 20 ℃; for 0.5h; Inert atmosphere;

1-[13C]acetonitrile; In diethyl ether; at 20 ℃; for 188h; Inert atmosphere;

DOI:10.1002/jlcr.1791

Reference yield: 82.0%

Benzyloxymethyl chloride (3587-60-8) + 1-[13C]-2',4',6'-trihydroxyacetophenone (1256496-52-2) → 1-[13C]-2',4'-bis(benzyloxymethyloxy)-6'-hydroxyacetophenone

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/jlcr.3571

upstream raw materials:

3,5-dihydroxyphenol

1-[13C]acetonitrile

[1-13C]acetyl chloride

Downstream raw materials:

(E)-[1-⁽¹³⁾C,3-⁽¹³⁾C]-(3,5-bis(benzyloxy)-2-(3-(3',4'-bis(benzyloxy)phenyl)allyl)phenoxy)(tert-butyldimethyl)silane

(1S,2S)-[1-⁽¹³⁾C,3-⁽¹³⁾C]-3-(2,4-bis(benzyloxy)-6-(tert-butyldimethylsilyloxy)phenyl)-1-(3',4'-bis(benzyloxy)phenyl)propane-1,2-diol

C₄₂⁽¹³⁾C₂H₃₈O₇

5,7,3',4'-tetra-O-benzyl-[2-⁽¹³⁾C,4-⁽¹³⁾C]-(2R,3S)-catechin

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1256496-52-2 1-[¹³C]-2',4',6'-trihydroxyacetophenone

Send

Send

Metric Ton KG G Pound L ML

Send

Send