(R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester

Base Information

Chemical Name:(R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester
CAS No.:1004791-11-0
Molecular Formula:C₁₈H₂₅NO₅
Molecular Weight:335.4
Hs Code.:

Synonyms:(R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester

Suppliers and Price of (R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester

There total 3 articles about (R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1004791-09-6
(R)-5-((R)-1-benzyloxyethyl)morpholine-3-one

: 24424-99-5
di-tert-butyl dicarbonate

: 1004791-11-0
(R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester

Guidance literature:: (R)-5-((R)-1-benzyloxyethyl)morpholine-3-one; di-tert-butyl dicarbonate; With dmap; triethylamine; In acetonitrile; at 20 ℃; for 4h;

With 1H-imidazole; In acetonitrile; at 20 ℃; for 0.5h;

Reference yield:

: 1004791-10-9
((2R,3R)-3-benzyloxy-2-t-butoxycarbonylaminobutoxy)acetic acid t-butyl ester

: 1004791-11-0
(R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

1.2: 1 h / 20 °C

1.3: 0 °C

2.1: triethylamine / dmap / acetonitrile / 4 h / 20 °C

2.2: 0.5 h / 20 °C

With triethylamine; trifluoroacetic acid; dmap; In dichloromethane; acetonitrile;

Reference yield:

: 79069-63-9,133565-43-2
tert-butyl [(2R,3R)-3-(benzyloxy)-1-hydroxybutan-2-yl]carbamate

: 1004791-11-0
(R)-3-((R)-1-benzyloxyethyl)-5-oxomorpholine-4-carboxylic acid t-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / water; toluene / 3 h / 0 °C

2.1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

2.2: 1 h / 20 °C

2.3: 0 °C

3.1: triethylamine / dmap / acetonitrile / 4 h / 20 °C

3.2: 0.5 h / 20 °C

With sodium hydroxide; triethylamine; trifluoroacetic acid; dmap; In dichloromethane; water; toluene; acetonitrile;