3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione

Base Information

• Chemical Name: 3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione
• CAS No.: 215871-90-2
• Molecular Formula: C₁₅H₁₇NO₃
• Molecular Weight: 259.305
• Mol file: 215871-90-2.mol

Synonyms:3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione

Chemical Property of 3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione

There total 9 articles about 3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Eth-(E)-ylidene-5,5-dimethoxy-1-(4-methoxy-benzyl)-3-methyl-pyrrolidin-2-one → 3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione (215871-90-2)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 0.166667h;

DOI:10.1246/cl.1995.713

Reference yield: 76.0%

3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-pyrrolidine-2,5-dione (215871-79-7) + methyl iodide (74-88-4) → 3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione (215871-90-2)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

DOI:10.1246/cl.1998.1001

Reference yield: 52.0%

Nitroethane (79-24-3) + 1-(4-Methoxy-benzyl)-3-methyl-pyrrole-2,5-dione (215871-89-9) → 3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione (215871-90-2) + 3-Eth-(Z)-ylidene-1-(4-methoxy-benzyl)-4-methyl-pyrrolidine-2,5-dione

Guidance literature:

With 1,8-diazabicyclo[5.4.0]undec-7-ene; at 0 ℃; for 1h;

DOI:10.1246/cl.1998.1001

upstream raw materials:

Nitroethane

1-(4-Methoxy-benzyl)-3-methyl-pyrrole-2,5-dione

3-Eth-(E)-ylidene-1-(4-methoxy-benzyl)-pyrrolidine-2,5-dione

methyl iodide

Downstream raw materials:

phycocyanobilin