Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-amino- (9CI)

Base Information

Chemical Name:Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-amino- (9CI)
CAS No.:737693-57-1
Molecular Formula:C₈H₁₃NO₂
Molecular Weight:155.197
Hs Code.:
Mol file:737693-57-1.mol

Synonyms:Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-amino- (9CI)

Suppliers and Price of Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-amino- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Aminobicyclo[2.2.1]heptane-1-carboxylicacid 97%
5g
$ 2600.00

Crysdot
4-Aminobicyclo[2.2.1]heptane-1-carboxylicacid 97%
1g
$ 1016.00

Total 9 raw suppliers

Chemical Property of Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-amino- (9CI)

Chemical Property:

Boiling Point:282.2±23.0 °C(Predicted)
PKA:4.21±0.10(Predicted)
PSA：63.32000
Density:1.354±0.06 g/cm3(Predicted)
LogP:1.43290

Purity/Quality:

97% ^*data from raw suppliers

4-Aminobicyclo[2.2.1]heptane-1-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-amino- (9CI)

There total 6 articles about Bicyclo[2.2.1]heptane-1-carboxylic acid, 4-amino- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1252672-36-8
4-(benzyloxycarbonylamino)bicyclo[2.2.1]heptane-1-carboxylic acid

: 737693-57-1
4-aminobicyclo[2.2.1]heptane-1-carboxylic acid

Guidance literature:: With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In methanol; for 10h; under 1551.49 Torr;

Reference yield:

: 4056-78-4,826-02-8
cyclopentane-1,3-dicarboxylic acid

: 737693-57-1
4-aminobicyclo[2.2.1]heptane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: sulfuric acid / 16 h / 7 - 12 °C / Reflux

2.1: N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine / tetrahydrofuran; hexanes / 2 h / -73 - -10 °C / Inert atmosphere

2.2: 16 h / -70 - 20 °C

3.1: water; sodium hydroxide / tetrahydrofuran; methanol / 16 h / 15 - 20 °C

3.2: 10 °C / pH ~ 4

4.1: diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine / toluene / 2 h / 10 - 110 °C

4.2: 40 h / 110 °C

5.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / methanol / 10 h / 1551.49 Torr

With hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; sulfuric acid; diphenyl phosphoryl azide; water; hydrogen; diisopropylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; palladium 10% on activated carbon; In tetrahydrofuran; methanol; hexanes; toluene;

Reference yield:

: 498-66-8
norborn-2-ene

: 737693-57-1
4-aminobicyclo[2.2.1]heptane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1.1: ruthenium trichloride; sodium periodate / water; ethyl acetate; acetonitrile / 5 - 39 °C / Industry scale

2.1: sulfuric acid / 16 h / 7 - 12 °C / Reflux

3.1: N,N,N,N,N,N-hexamethylphosphoric triamide; n-butyllithium; diisopropylamine / tetrahydrofuran; hexanes / 2 h / -73 - -10 °C / Inert atmosphere

3.2: 16 h / -70 - 20 °C

4.1: water; sodium hydroxide / tetrahydrofuran; methanol / 16 h / 15 - 20 °C

4.2: 10 °C / pH ~ 4

5.1: diphenyl phosphoryl azide; N-ethyl-N,N-diisopropylamine / toluene / 2 h / 10 - 110 °C

5.2: 40 h / 110 °C

6.1: hydrogenchloride; hydrogen / palladium 10% on activated carbon / methanol / 10 h / 1551.49 Torr

With hydrogenchloride; N,N,N,N,N,N-hexamethylphosphoric triamide; ruthenium trichloride; sodium periodate; n-butyllithium; sulfuric acid; diphenyl phosphoryl azide; water; hydrogen; diisopropylamine; N-ethyl-N,N-diisopropylamine; sodium hydroxide; palladium 10% on activated carbon; In tetrahydrofuran; methanol; hexanes; water; ethyl acetate; toluene; acetonitrile;