4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine

Base Information

Chemical Name:4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine
CAS No.:1011264-40-6
Molecular Formula:C₂₅H₂₅N₃O₂
Molecular Weight:399.492
Hs Code.:

Synonyms:4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine

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Chemical Property of 4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine

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Technology Process of 4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine

There total 2 articles about 4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₅H₂₇N₃O₃

: 1011264-40-6
4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine

Guidance literature:: With pyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 20 ℃; for 19h;

Reference yield:

: 849226-46-6
2-ethyl-6-methyl-isonicotinic acid

: 944327-04-2
4-benzyloxy-3,5-dimethyl-benzoic acid hydrazide

: 1011264-40-6
4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine

Guidance literature:: 2-ethyl-6-methyl-isonicotinic acid; 4-benzyloxy-3,5-dimethyl-benzoic acid hydrazide; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 3h;

With pyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 20 ℃; for 19h;

In dichloromethane; for 0.5h;

Reference yield:

: 1011264-40-6
4-[5-(4-benzyloxy-3,5-dimethyl-phenyl)-[1,3,4]oxadiazol-2-yl]-2-ethyl-6-methyl-pyridine

: 4-[5-(2-ethyl-6-methyl-pyridin-4-yl)-[1,3,4]oxadiazol-2-yl]-2,6-dimethyl-phenol

Guidance literature:: With formic acid; hydrogen; palladium 10% on activated carbon; In tetrahydrofuran; methanol; at 20 ℃; for 15h; under 750.075 Torr;