2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

Base Information

• Chemical Name: 2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside
• CAS No.: 1388133-91-2
• Molecular Formula: C₉₁H₇₈N₄O₂₆
• Molecular Weight: 1643.63
• Mol file: 1388133-91-2.mol

Synonyms:2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

Chemical Property of 2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

There total 1 articles about 2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl 4-deoxy-4-azido-2,3,6-tri-O-benzoyl-β-D-thio-glucopyranoside (1388133-63-8) + 2-(N-benzyloxycarbonyl)-aminoethyl (2,3,4-tri-O-benzoyl-6-O-chloroacetyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside (1388133-90-1) → 2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside (1388133-91-2)

Guidance literature:

2-(N-benzyloxycarbonyl)-aminoethyl (2,3,4-tri-O-benzoyl-6-O-chloroacetyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside; With 2,6-dimethylpyridine; thiourea; In methanol; dichloromethane; for 96h;

ethyl 4-deoxy-4-azido-2,3,6-tri-O-benzoyl-β-D-thio-glucopyranoside; With N-iodo-succinimide; silver trifluoromethanesulfonate; In dichloromethane; at 0 - 20 ℃; for 1h; Molecular sieve;

DOI:10.1016/j.tet.2012.05.118

Reference yield: 62.0%

BOC-glycine (4530-20-5) + 2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside (1388133-91-2) → 2-(N-benzyloxycarbonyl)-aminoethyl (4-deoxy-4-N-tert-butyloxycarbonyl-glycyl-β-D-glucopyranosyl)-(1->6)-(α-D-mannopyranosyl)-(1->6)-α-D-mannopyranoside

Guidance literature:

2-(N-benzyloxycarbonyl)-aminoethyl (4-N-azido-4-deoxy-2,3,6-tri-O-benzoyl-β-D-glucopyranosyl)-(1->6)-(2,3,4-tri-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside; With sodium methylate; In methanol; dichloromethane;

In methanol; dichloromethane;

BOC-glycine; Further stages;

DOI:10.1016/j.tet.2012.05.118

upstream raw materials:

ethyl 4-deoxy-4-azido-2,3,6-tri-O-benzoyl-β-D-thio-glucopyranoside

2-(N-benzyloxycarbonyl)-aminoethyl (2,3,4-tri-O-benzoyl-6-O-chloroacetyl-α-D-mannopyranosyl)-(1->6)-2,3,4-tri-O-benzoyl-α-D-mannopyranoside