Methyl 2-fluoro-5-sulfamoylbenzoate

Base Information

Chemical Name:Methyl 2-fluoro-5-sulfamoylbenzoate
CAS No.:1099052-48-8
Molecular Formula:C₈H₈FNO₄S
Molecular Weight:233.22
Hs Code.:
European Community (EC) Number:830-114-3

Synonyms:methyl 2-fluoro-5-sulfamoylbenzoate;1099052-48-8;SCHEMBL3362967;WNDPEZPNAUBWAD-UHFFFAOYSA-N;methyl2-fluoro-5-sulfamoylbenzoate;GS1167;AKOS007963451;CS-0244651;EN300-28735;Z24199854

Suppliers and Price of Methyl 2-fluoro-5-sulfamoylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 2-fluoro-5-sulfamoylbenzoate

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:233.01580707
Heavy Atom Count:15
Complexity:337

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=C(C=CC(=C1)S(=O)(=O)N)F

Technology Process of Methyl 2-fluoro-5-sulfamoylbenzoate

There total 2 articles about Methyl 2-fluoro-5-sulfamoylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 112887-25-9
5-(aminosulfonyl)-2-fluorobenzoic acid

: 74-88-4
methyl iodide

: 1099052-48-8
methyl 2-fluoro-5-sulfamoylbenzoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1021/acs.jmedchem.0c00511

Reference yield:

: 37098-75-2
2-fluoro-5-chlorosulfonylbenzoic acid

: 1099052-48-8
methyl 2-fluoro-5-sulfamoylbenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium hydroxide / dichloromethane / 0 - 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C

With ammonium hydroxide; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/acs.jmedchem.0c00511