N-hydroxy-4-(naphthalen-1-yl)benzamide

Base Information

Chemical Name:N-hydroxy-4-(naphthalen-1-yl)benzamide
CAS No.:106359-61-9
Molecular Formula:C₁₇H₁₃NO₂
Molecular Weight:263.296
Hs Code.:
European Community (EC) Number:695-514-0
ChEMBL ID:CHEMBL156887
Nikkaji Number:J275.029E
Pharos Ligand ID:U9VK53CF28RP

Synonyms:N-hydroxy-4-(naphthalen-1-yl)benzamide;106359-61-9;NHNB;N-hydroxy-4-naphthalen-1-ylbenzamide;CHEMBL156887;4-Naphthalen-1-Yl-~{n}-Oxidanyl-Benzamide;n-hydroxy-4-(1-naphthalenyl)-benzamide;5YA;N-Hydroxy-4-naphthalen-1-yl-benzamide;SCHEMBL10361645;BDBM50015149;N-Hydroxy-4-(naphthalene-1-yl)benzamide

Suppliers and Price of N-hydroxy-4-(naphthalen-1-yl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of N-hydroxy-4-(naphthalen-1-yl)benzamide

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:263.094628657
Heavy Atom Count:20
Complexity:336

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=CC=C2C3=CC=C(C=C3)C(=O)NO

Technology Process of N-hydroxy-4-(naphthalen-1-yl)benzamide

There total 8 articles about N-hydroxy-4-(naphthalen-1-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90-11-9
1-Bromonaphthalene

: 106359-61-9
N-hydroxy-4-(naphthalene-1-yl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) a) tert-butyllithium, zinc chloride, b) diisobutylammonium hydride, palladium bis(triphenylphosphine) dichloride / tetrahydrofuran / 1 h / -78 - 20 °C

2: LiOH / propan-2-ol; H₂O

3: 1.) DMF, (COCl)2, 2.) hydroxylamine hydrochloride, Et₃N / 1.) CH₂Cl₂, 0 deg C, 40 min, 2.) CH₂Cl₂, THF, H₂O, 30 min

With lithium hydroxide; bis(triphenylphosphine)palladium(II) dichloride; oxalyl dichloride; Diisobutylammonium hydride; hydroxylamine hydrochloride; tert.-butyl lithium; triethylamine; N,N-dimethyl-formamide; zinc(II) chloride; In tetrahydrofuran; water; isopropyl alcohol;
DOI:10.1021/jm00386a022

Reference yield:

: 619-44-3
methyl 4-iodobenzoate

: 106359-61-9
N-hydroxy-4-(naphthalene-1-yl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) a) tert-butyllithium, zinc chloride, b) diisobutylammonium hydride, palladium bis(triphenylphosphine) dichloride / tetrahydrofuran / 1 h / -78 - 20 °C

2: LiOH / propan-2-ol; H₂O

3: 1.) DMF, (COCl)2, 2.) hydroxylamine hydrochloride, Et₃N / 1.) CH₂Cl₂, 0 deg C, 40 min, 2.) CH₂Cl₂, THF, H₂O, 30 min

With lithium hydroxide; bis(triphenylphosphine)palladium(II) dichloride; oxalyl dichloride; Diisobutylammonium hydride; hydroxylamine hydrochloride; tert.-butyl lithium; triethylamine; N,N-dimethyl-formamide; zinc(II) chloride; In tetrahydrofuran; water; isopropyl alcohol;
DOI:10.1021/jm00386a022

Reference yield:

: 229467-26-9
4-naphthalene-1-ylbenzoic acid methyl ester

: 106359-61-9
N-hydroxy-4-(naphthalene-1-yl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: LiOH / propan-2-ol; H₂O

2: 1.) DMF, (COCl)2, 2.) hydroxylamine hydrochloride, Et₃N / 1.) CH₂Cl₂, 0 deg C, 40 min, 2.) CH₂Cl₂, THF, H₂O, 30 min

With lithium hydroxide; oxalyl dichloride; hydroxylamine hydrochloride; triethylamine; N,N-dimethyl-formamide; In water; isopropyl alcohol;
DOI:10.1021/jm00386a022