3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propionic acid trifluoroacetate

Base Information

Chemical Name:3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propionic acid trifluoroacetate
CAS No.:1311291-00-5
Molecular Formula:C₂HF₃O₂*C₁₅H₁₃FN₂O₄S
Molecular Weight:450.368
Hs Code.:

Synonyms:3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propionic acid trifluoroacetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propionic acid trifluoroacetate

Chemical Property:

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Technology Process of 3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propionic acid trifluoroacetate

There total 2 articles about 3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propionic acid trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1311290-63-7
4-amidino-2-fluorophenol trifluoroacetate

: 1892-57-5,754131-18-5
N-(3-dimethylaminopropyl)-N-ethylcarbodiimide

: 1311291-00-5
3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propionic acid trifluoroacetate

Guidance literature:: With palladium dihydroxide; In pyridine; methanol; chloroform;

Reference yield:

: 405-04-9
3-fluoro-4-hydroxybenzonitrile

: 1311291-00-5
3-[5-(4-amidino-2-fluorophenoxycarbonyl)thiophen-2-yl]propionic acid trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride; ammonium carbonate; trifluoroacetic acid / ethanol; 1,4-dioxane

2: palladium dihydroxide / methanol; pyridine; chloroform

With ammonium carbonate; hydrogenchloride; palladium dihydroxide; trifluoroacetic acid; In 1,4-dioxane; pyridine; methanol; ethanol; chloroform;