c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid

Base Information

• Chemical Name: c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid
• CAS No.: 77803-82-8
• Molecular Formula: BrH*C₈H₁₄BrNO₃
• Molecular Weight: 333.02
• Mol file: 77803-82-8.mol

Synonyms:c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid

Chemical Property of c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid

There total 3 articles about c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(+/-)-2-Oxa-3-azabicyclo[2.2.2]oct-5-ene hydrochloride (56239-25-9) → c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid (77803-82-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / Zn, conc. HCl / H₂O / 8 h / 0 - 10 °C

2: 70 percent / pyridine

3: 1.) Br₂, 2.) H₂O / 1.) glacial acetic acid, 45min; 2.) 30 min, room temp.

With hydrogenchloride; water; bromine; zinc; In pyridine; water;

Reference yield:

(1S*,4R*)-4-aminocyclohex-2-enol (77803-77-1,96093-87-7,131321-46-5) → c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid (77803-82-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / pyridine

2: 1.) Br₂, 2.) H₂O / 1.) glacial acetic acid, 45min; 2.) 30 min, room temp.

With water; bromine; In pyridine;

Reference yield:

N-(cis-4-Hydroxy-2-cyclohexen-1-yl)acetamid (77803-79-3) → c-2-Acetoxy-t-3-brom-c-4-hydroxy-r-1-cyclohexylammoniumbromid (77803-82-8)

Guidance literature:

With water; bromine; Yield given. Multistep reaction; 1.) glacial acetic acid, 45min; 2.) 30 min, room temp.;

upstream raw materials:

N-(cis-4-Hydroxy-2-cyclohexen-1-yl)acetamid

(+/-)-2-Oxa-3-azabicyclo[2.2.2]oct-5-ene hydrochloride

(1S*,4R*)-4-aminocyclohex-2-enol

Downstream raw materials:

N-(t-3-Brom-c-2,c-4-dihydroxy-r-1-cyclohexyl)acetamid