N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide

Base Information

• Chemical Name: N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide
• CAS No.: 1453860-56-4
• Molecular Formula: C₃₃H₄₈N₂O₃
• Molecular Weight: 520.756
• Mol file: 1453860-56-4.mol

Synonyms:N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide

Chemical Property of N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide

There total 4 articles about N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

N,N-dimethyl-3,12-dioxo-7-deoxycholic amide (1453860-48-4) + O-benzylhydoxylamine hydrochloride (2687-43-6) → N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide (1453860-56-4)

Guidance literature:

With sodium acetate; In ethanol; at 70 ℃; for 3h;

DOI:10.3390/molecules18077436

Reference yield:

Deoxycholic acid (83-44-3) → N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide (1453860-56-4)

Guidance literature:

Multi-step reaction with 4 steps

1: Jones reagent / acetone / 0 °C

2: pyridine; oxalyl dichloride / toluene / 2 h / Cooling with ice

3: toluene / 0.17 h / 0 °C

4: sodium acetate / ethanol / 3 h / 70 °C

With pyridine; Jones reagent; oxalyl dichloride; sodium acetate; In ethanol; acetone; toluene;

DOI:10.3390/molecules18077436

Reference yield:

3,12-dioxo-7-deoxycholic acid (2958-05-6) → N,N-dimethyl-3-O-benzyloximino-12-oxo-7-deoxycholic amide (1453860-56-4)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine; oxalyl dichloride / toluene / 2 h / Cooling with ice

2: toluene / 0.17 h / 0 °C

3: sodium acetate / ethanol / 3 h / 70 °C

With pyridine; oxalyl dichloride; sodium acetate; In ethanol; toluene;

DOI:10.3390/molecules18077436

upstream raw materials:

Deoxycholic acid

3,12-dioxo-7-deoxycholic acid

N,N-dimethyl-3,12-dioxo-7-deoxycholic amide

O-benzylhydoxylamine hydrochloride