1-((1R,2R)-2-aminocyclohexyl)-3-((1S,2S)-2-(dimethyl amino)cyclohexyl)thiourea

Base Information

Chemical Name:1-((1R,2R)-2-aminocyclohexyl)-3-((1S,2S)-2-(dimethyl amino)cyclohexyl)thiourea
CAS No.:1384718-12-0
Molecular Formula:C₁₅H₃₀N₄S
Molecular Weight:298.496
Hs Code.:

Synonyms:1-((1R,2R)-2-aminocyclohexyl)-3-((1S,2S)-2-(dimethyl amino)cyclohexyl)thiourea

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Chemical Property of 1-((1R,2R)-2-aminocyclohexyl)-3-((1S,2S)-2-(dimethyl amino)cyclohexyl)thiourea

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Technology Process of 1-((1R,2R)-2-aminocyclohexyl)-3-((1S,2S)-2-(dimethyl amino)cyclohexyl)thiourea

There total 2 articles about 1-((1R,2R)-2-aminocyclohexyl)-3-((1S,2S)-2-(dimethyl amino)cyclohexyl)thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1384718-40-4
C₂₀H₃₈N₄O₂S

: 1384718-12-0
1-((1R,2R)-2-aminocyclohexyl)-3-((1S,2S)-2-(dimethyl amino)cyclohexyl)thiourea

Guidance literature:: C₂₀H₃₈N₄O₂S; With hydrogenchloride; In 1,4-dioxane;

With sodium hydroxide; In 1,4-dioxane; water; pH=13 - 14;
DOI:10.1016/j.tet.2012.05.061

Reference yield:

: 1030603-66-7
tert-butyl (1R,2R)-2-isothio-cyanatocyclohexylcarbamate

: 894493-95-9
(1S,2S)-N,N-dimethylcyclohexane-1,2-diamine

: 1384718-12-0
1-((1R,2R)-2-aminocyclohexyl)-3-((1S,2S)-2-(dimethyl amino)cyclohexyl)thiourea

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 12 h

2.1: hydrogenchloride / 1,4-dioxane

2.2: pH 13 - 14

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.tet.2012.05.061