Technology Process of (-)-6,7-epoxy-8-(benzyloxy)geranyl alcohol
There total 4 articles about (-)-6,7-epoxy-8-(benzyloxy)geranyl alcohol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium methylate; tetra-(n-butyl)ammonium iodide;
In
methanol;
for 12h;
Ambient temperature;
DOI:10.1021/jo00256a007
- Guidance literature:
-
Multi-step reaction with 4 steps
2: 1.) L-(+)-diisopropyl tartrate (L-(+)-DIPT), Ti(OiPr), tert-butyl hydroperoxide (TBHP), 3-Angstroem molecular sieves, 2.) triethanolamine / 1.) CH2Cl2, 2,2,4-trimethylpentane, -30 deg C, 3.5 h, 2.) -15 deg C, 0.5 h
3: 1.) NaH, 2.) n-Bu4NI / 1.) THF, RT, 20 min, 2.) THF, RT, 5 h
4: 99 percent / CH3ONa, n-Bu4NI / methanol / 12 h / Ambient temperature
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; triethanolamine; L-(+)-diisopropyl tartrate; 3 A molecular sieve; sodium methylate; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
methanol;
DOI:10.1021/jo00256a007
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) L-(+)-diisopropyl tartrate (L-(+)-DIPT), Ti(OiPr), tert-butyl hydroperoxide (TBHP), 3-Angstroem molecular sieves, 2.) triethanolamine / 1.) CH2Cl2, 2,2,4-trimethylpentane, -30 deg C, 3.5 h, 2.) -15 deg C, 0.5 h
2: 1.) NaH, 2.) n-Bu4NI / 1.) THF, RT, 20 min, 2.) THF, RT, 5 h
3: 99 percent / CH3ONa, n-Bu4NI / methanol / 12 h / Ambient temperature
With
titanium(IV) isopropylate; tert.-butylhydroperoxide; triethanolamine; L-(+)-diisopropyl tartrate; 3 A molecular sieve; sodium methylate; tetra-(n-butyl)ammonium iodide; sodium hydride;
In
methanol;
DOI:10.1021/jo00256a007
