88218-65-9Relevant articles and documents
Biomimetic Syntheses of Analogs of Hongoquercin A and B by Late-Stage Derivatization
Mies, Thomas,White, Andrew J. P.,Parsons, Philip J.,Barrett, Anthony G. M.
, p. 1802 - 1817 (2021/01/13)
The hongoquercins are tetracyclic meroterpenoid natural products with the trans-transoid decalin-dihydrobenzopyran ring system, which display a range of different bioactivities. In this study, the syntheses of a range of hongoquercins using gold-catalyzed enyne cyclization reactions and further derivatization are described. The parent enyne resorcylate precursors were synthesized biomimetically from the corresponding dioxinone keto ester via regioselective acylation, Tsuji-Trost allylic decarboxylative rearrangement, and aromatization. The dioxinone keto ester 12 was prepared in 6 steps from geraniol using allylic functionalization and alkyne synthesis.
A simple and selective method for the O-AcCl removal using sodium borohydride
Villedieu, Emmanuelle,Lopin-Bon, Chrystel,Berteina-Raboin, Sabine
scheme or table, p. 2115 - 2118 (2010/06/14)
A deprotection of chloroacetylated alcohols using NaBH4 is reported. The free alcohols are obtained in excellent yields. The reaction was performed on primary, secondary, alkyl, allyl, benzylic alcohols and phenols. The compatibility of the method with other sensitive or protective groups is demonstrated.
Furans in synthesis. 8. Formal total syntheses of (±)- and (+)-aphidicolin
Tanis,Chuang,Head
, p. 4929 - 4938 (2007/10/02)
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