4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon

Base Information

• Chemical Name: 4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon
• CAS No.: 74362-01-9
• Molecular Formula: C₁₇H₁₇ClN₂O₃
• Molecular Weight: 332.787
• Mol file: 74362-01-9.mol

Synonyms:4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon

Chemical Property of 4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon

There total 3 articles about 4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-chlorophenyl)-3-(pyridin-4-yl)prop-2-en-1-one (40665-23-4) + 2-nitropropane (79-46-9) → 4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon (74362-01-9)

Guidance literature:

With sodium methylate; In methanol; at 40 ℃; Yield given;

DOI:10.1002/hlca.19800630313

Reference yield:

pyridine-4-carbaldehyde (872-85-5) → 4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon (74362-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 percent NaOH solution (in water) / Ambient temperature

2: NaOMe / methanol / 40 °C

With sodium hydroxide; sodium methylate; In methanol;

DOI:10.1002/hlca.19800630313

Reference yield:

para-chloroacetophenone (99-91-2) → 4'-Chlor-4-methyl-4-nitro-3-(4-pyridyl)valerophenon (74362-01-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1 percent NaOH solution (in water) / Ambient temperature

2: NaOMe / methanol / 40 °C

With sodium hydroxide; sodium methylate; In methanol;

DOI:10.1002/hlca.19800630313

upstream raw materials:

1-(4-chlorophenyl)-3-(pyridin-4-yl)prop-2-en-1-one

2-nitropropane

pyridine-4-carbaldehyde

para-chloroacetophenone

Downstream raw materials:

4-(2'-(p-Chlorphenyl)-5',5'-dimethyl-1'-pyrrolin-4'-yl)pyridin-1'-oxid