3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine

Base Information

• Chemical Name: 3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine
• CAS No.: 354145-88-3
• Molecular Formula: C₄₉H₄₁Br₄NO₆
• Molecular Weight: 1059.48
• Mol file: 354145-88-3.mol

Synonyms:3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine

Chemical Property of 3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine

There total 2 articles about 3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-{3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzyl}-isoindole-1,3-dione (354145-87-2) → 3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine (354145-88-3)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; ethanol; for 2h; Heating;

DOI:10.1021/ja010257c

Reference yield:

C49H39Br5O6 (134868-86-3) → 3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine (354145-88-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / K₂CO₃ / acetonitrile / 3 h / Heating

2: 96 percent / H₂NNH₂*H₂O / ethanol; tetrahydrofuran / 2 h / Heating

With potassium carbonate; hydrazine hydrate; In tetrahydrofuran; ethanol; acetonitrile;

DOI:10.1021/ja010257c

Reference yield: 79.0%

4-diphenylphosphanobenzoic acid (2129-31-9) + 3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzylamine (354145-88-3) → N-{3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzyl}-4-diphenylphosphanyl-benzamide (352212-71-6)

Guidance literature:

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In chloroform; at 20 ℃; for 3h;

DOI:10.1021/ja010257c

upstream raw materials:

2-{3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzyl}-isoindole-1,3-dione

C₄₉H₃₉Br₅O₆

Downstream raw materials:

N-{3,5-bis-[3,5-bis-(4-bromo-benzyloxy)-benzyloxy]-benzyl}-4-diphenylphosphanyl-benzamide