3-(3-hydroxyphenyl)quinuclidine hydrobromide

Base Information

Chemical Name:3-(3-hydroxyphenyl)quinuclidine hydrobromide
CAS No.:79412-64-9
Molecular Formula:BrH*C₁₃H₁₇NO
Molecular Weight:284.196
Hs Code.:

Synonyms:3-(3-hydroxyphenyl)quinuclidine hydrobromide

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Chemical Property of 3-(3-hydroxyphenyl)quinuclidine hydrobromide

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Technology Process of 3-(3-hydroxyphenyl)quinuclidine hydrobromide

There total 4 articles about 3-(3-hydroxyphenyl)quinuclidine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 79412-63-8
3-(3-hydroxyphenyl)quinuclidin-2-ene hydrobromide

: 79412-64-9
3-(3-hydroxyphenyl)quinuclidine hydrobromide

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00144a021

Reference yield:

: 3731-38-2
3-Quinuclidinone

: 79412-64-9
3-(3-hydroxyphenyl)quinuclidine hydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: 33 percent / tetrahydrofuran / 24 h / Ambient temperature

2: 46 percent / 48percent aq. HBr / 2 h / 120 °C

3: 47 percent / H₂ / 5percent Pd/C / methanol

With hydrogen bromide; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1021/jm00144a021

Reference yield:

: 36282-40-3
(3-methoxyphenyl)magnesium bromide

: 79412-64-9
3-(3-hydroxyphenyl)quinuclidine hydrobromide

Guidance literature:: Multi-step reaction with 3 steps

1: 33 percent / tetrahydrofuran / 24 h / Ambient temperature

2: 46 percent / 48percent aq. HBr / 2 h / 120 °C

3: 47 percent / H₂ / 5percent Pd/C / methanol

With hydrogen bromide; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1021/jm00144a021