(S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine

Base Information

• Chemical Name: (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine
• CAS No.: 444643-02-1
• Molecular Formula: C₁₇H₁₈F₃N
• Molecular Weight: 293.332
• Mol file: 444643-02-1.mol

Synonyms:(S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine

Chemical Property of (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine

There total 8 articles about (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1-phenyl-N-{(S)-1-[2-(trifluoromethyl)phenyl]ethyl}ethanamine (437762-07-7) → (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine (444643-02-1) + (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃;

DOI:10.1021/ol034014w

Reference yield:

(S)-1-phenyl-ethylamine (2627-86-3) → (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine (444643-02-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / zinc chloride / toluene / 44 h / Heating

2: sodium borohydride / methanol / 0 °C

With sodium tetrahydroborate; zinc(II) chloride; In methanol; toluene;

DOI:10.1021/ol034014w

Reference yield:

1-(2-(trifluoromethyl)phenyl)ethan-1-one (17408-14-9) → (S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine (444643-02-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / zinc chloride / toluene / 44 h / Heating

2: sodium borohydride / methanol / 0 °C

With sodium tetrahydroborate; zinc(II) chloride; In methanol; toluene;

DOI:10.1021/ol034014w

upstream raw materials:

(S)-1-phenyl-N-{(S)-1-[2-(trifluoromethyl)phenyl]ethyl}ethanamine

(S)-1-phenyl-ethylamine

1-(2-(trifluoromethyl)phenyl)ethan-1-one

C₈H₆O₄*C₁₇H₁₈F₃N

Downstream raw materials:

(S)-1-(2-(trifluoromethyl)phenyl)ethan-1-amine hydrochloride

(S)-2,2,2-trifluoro-N-(1-(2-(trifluoromethyl)phenyl)ethyl)acetamide

(S)-α-(o-(trifluoromethyl)phenyl)ethylamine