(S)-1-[2-(Trifluoromethyl)phenyl]ethylamine

Base Information

Chemical Name:(S)-1-[2-(Trifluoromethyl)phenyl]ethylamine
CAS No.:127733-39-5
Molecular Formula:C9H10F3N
Molecular Weight:189.18
Hs Code.:2921490090
European Community (EC) Number:691-809-3
DSSTox Substance ID:DTXSID10925972
Nikkaji Number:J1.895.301C
Wikidata:Q72512357
Mol file:127733-39-5.mol

Synonyms:127733-39-5;(S)-1-[2-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE;(1S)-1-[2-(trifluoromethyl)phenyl]ethanamine;(S)-1-(2-(TRIFLUOROMETHYL)PHENYL)ETHANAMINE;(1S)-1-[2-(Trifluoromethyl)phenyl]ethylamine;(1S)-1-[2-(trifluoromethyl)phenyl]ethan-1-amine;(s)-1-(2-(trifluoromethyl)phenyl)ethylamine;(S)-1-[2-(Trifluoromethyl)phenyl]ethanamine;(S)-1-(2-(trifluoromethyl)phenyl)ethan-1-amine;SCHEMBL334979;Benzenemethanamine, -methyl-2-(trifluoromethyl)-, (S)-;DTXSID10925972;DPLIMKBGTYIUCB-LURJTMIESA-N;AMY32662;MFCD03093002;AKOS015840052;AS-78662;CS-0000265;EN300-62409;A805740;(S)-1-[2-(Trifluoromethyl)phenyl]ethylamine, AldrichCPR;Benzenemethanamine, a-methyl-2-(trifluoromethyl)-, (aS)-

Suppliers and Price of (S)-1-[2-(Trifluoromethyl)phenyl]ethylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-1-(2-(Trifluoromethyl)Phenyl)Ethanamine
10mg
$ 45.00

TRC
(S)-1-(2-(Trifluoromethyl)Phenyl)Ethanamine
50mg
$ 175.00

SynQuest Laboratories
(S)-1-[2-(Trifluoromethyl)phenyl]ethylamine 98%
1 g
$ 475.00

SynQuest Laboratories
(S)-1-[2-(Trifluoromethyl)phenyl]ethylamine 98%
100 mg
$ 95.00

SynQuest Laboratories
(S)-1-[2-(Trifluoromethyl)phenyl]ethylamine 98%
250 mg
$ 195.00

AstaTech
(S)-1-(2-(TRIFLUOROMETHYL)PHENYL)ETHANAMINE 95%
5 / G
$ 1662.00

AstaTech
(S)-1-(2-(TRIFLUOROMETHYL)PHENYL)ETHANAMINE 95%
0.25 / G
$ 190.00

AstaTech
(S)-1-(2-(TRIFLUOROMETHYL)PHENYL)ETHANAMINE 95%
1 / G
$ 475.00

Apolloscientific
(1S)-1-[2-(Trifluoromethyl)phenyl]ethylamine 98%
100mg
$ 261.00

Apolloscientific
(1S)-1-[2-(Trifluoromethyl)phenyl]ethylamine 98%
250mg
$ 530.00

Total 24 raw suppliers

Chemical Property of (S)-1-[2-(Trifluoromethyl)phenyl]ethylamine

Chemical Property:

Vapor Pressure:0.401mmHg at 25°C
Refractive Index:1.465
Boiling Point:196.326 °C at 760 mmHg
PKA:8.25±0.10(Predicted)
Flash Point:78.827 °C
PSA：26.02000
Density:1.181 g/cm³
LogP:3.42540
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:189.07653381
Heavy Atom Count:13
Complexity:167

Purity/Quality:

99%, ^*data from raw suppliers

(S)-1-(2-(Trifluoromethyl)Phenyl)Ethanamine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1C(F)(F)F)N
Isomeric SMILES:C[C@@H](C1=CC=CC=C1C(F)(F)F)N

Technology Process of (S)-1-[2-(Trifluoromethyl)phenyl]ethylamine

There total 11 articles about (S)-1-[2-(Trifluoromethyl)phenyl]ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 444643-02-1
(S)-1-phenyl-N-((S)-1-(2-(trifluoromethyl)phenyl)ethyl)ethanamine

: 127733-39-5,273384-78-4
(S)-α-(o-(trifluoromethyl)phenyl)ethylamine

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In methanol; at 60 ℃; for 24h; under 11251.1 Torr; optical yield given as %ee;
DOI:10.1002/adsc.201100250

Reference yield: 70.0%

: 865815-09-4
(S)-1-(2-(trifluoromethyl)phenyl)ethan-1-amine hydrochloride

: 127733-39-5,273384-78-4
(S)-α-(o-(trifluoromethyl)phenyl)ethylamine

Guidance literature:: With sodium hydroxide; In water; at 20 ℃; for 1h;

Reference yield:

: 17408-14-9
1-(2-(trifluoromethyl)phenyl)ethan-1-one

: 127733-39-5,273384-78-4
(S)-α-(o-(trifluoromethyl)phenyl)ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / zinc chloride / toluene / 44 h / Heating

2: sodium borohydride / methanol / 0 °C

3: hydrogen; acetic acid; water / 5 percent Pd/C NX-type / methanol / 12 h / 60 °C / 3750.3 Torr

With sodium tetrahydroborate; water; hydrogen; acetic acid; zinc(II) chloride; palladium on activated charcoal; In methanol; toluene;
DOI:10.1021/ol034014w