(S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane

Base Information

• Chemical Name: (S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane
• CAS No.: 1245286-13-8
• Molecular Formula: C₅₇H₆₅BF₄O₄Si₂
• Molecular Weight: 957.116
• Mol file: 1245286-13-8.mol

Synonyms:(S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane

Chemical Property of (S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane

There total 1 articles about (S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol (1245286-02-5) + triisopropylsilyl trifluoromethanesulfonate (80522-42-5) → (S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane (1245286-13-8)

Guidance literature:

In dichloromethane; at 0 ℃; Inert atmosphere;

DOI:10.1021/ol101789g

Reference yield: 69.0%

(S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane (1245286-13-8) + pinacol vinylboronate (75927-49-0) → (S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R,E)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane (1245286-24-1)

Guidance literature:

With Hoveyda-Grubbs catalyst second generation; 2,3,5,6-tetrafluoro-1,4-benzoquinone; In toluene; at 80 ℃; for 24h; optical yield given as %de; Inert atmosphere;

DOI:10.1021/ol101789g

upstream raw materials:

(3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol

triisopropylsilyl trifluoromethanesulfonate

Downstream raw materials:

(S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R,E)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane