(3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol

Base Information

• Chemical Name: (3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol
• CAS No.: 1245286-02-5
• Molecular Formula: C₄₈H₄₅BF₄O₄Si
• Molecular Weight: 800.773
• Mol file: 1245286-02-5.mol

Synonyms:(3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol

Chemical Property of (3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol

There total 1 articles about (3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C49H54B2F4O2 + 3-(tert-butyldiphenylsilyloxy)-1-propanal (112897-03-7) → (3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol (1245286-02-5)

Guidance literature:

C₄₉H₅₄B₂F₄O₂; 3-(tert-butyldiphenylsilyloxy)-1-propanal; In dichloromethane; at -78 ℃; for 6h; Inert atmosphere; Glove box;

With methanol; In dichloromethane; for 4h; Inert atmosphere; Glove box;

DOI:10.1021/ol101789g

Reference yield: 84.0%

(3S,4R)-1-(tert-butyldiphenylsilyloxy)-4-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)hex-5-en-3-ol (1245286-02-5) + triisopropylsilyl trifluoromethanesulfonate (80522-42-5) → (S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane (1245286-13-8)

Guidance literature:

In dichloromethane; at 0 ℃; Inert atmosphere;

DOI:10.1021/ol101789g

upstream raw materials:

3-(tert-butyldiphenylsilyloxy)-1-propanal

Downstream raw materials:

(S)-9,9-diisopropyl-2,2,10-trimethyl-3,3-diphenyl-7-((R)-1-(4,4,5,5-tetrakis(4-fluorophenyl)-1,3,2-dioxaborolan-2-yl)allyl)-4,8-dioxa-3,9-disilaundecane