N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide

Base Information

Chemical Name:N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide
CAS No.:1018473-09-0
Molecular Formula:C₂₄H₂₁F₃N₆OS
Molecular Weight:498.532
Hs Code.:

Synonyms:N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide

Suppliers and Price of N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide

There total 2 articles about N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 876322-59-7
N-(3-bromo-4-methylphenyl)-3-(trifluoromethyl)benzamide

: 1018473-08-9
2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamine

: 1018473-09-0
N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide

Guidance literature:: With caesium carbonate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 150 ℃; for 1h; Irradiation;

Reference yield:

: 1018473-11-4
4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamine

: 1018473-09-0
N-(4-methyl-3-(2-methyl-4-(6-methylsulfanylpyrimidin-4-yl)-2H-pyrazol-3-ylamino)-phenyl)-3-trifluoromethylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium methylate / methanol / 0.5 h

1.2: 20 °C

2.1: caesium carbonate / palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene / 1,4-dioxane / 1 h / 150 °C / Irradiation

With sodium methylate; caesium carbonate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; methanol;