benzophenone α-chlorophenylacetylhydrazone

Base Information

• Chemical Name: benzophenone α-chlorophenylacetylhydrazone
• CAS No.: 79289-08-0
• Molecular Formula: C₂₁H₁₇ClN₂O
• Molecular Weight: 348.832
• Mol file: 79289-08-0.mol

Synonyms:benzophenone α-chlorophenylacetylhydrazone

Chemical Property of benzophenone α-chlorophenylacetylhydrazone

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzophenone α-chlorophenylacetylhydrazone

There total 1 articles about benzophenone α-chlorophenylacetylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

benzophenone hydrazone (5350-57-2) + α-chlorophenylacetyl chloride (2912-62-1) → benzophenone α-chlorophenylacetylhydrazone (79289-08-0)

Guidance literature:

With pyridine; In dichloromethane; for 0.25h; Heating;

DOI:10.1021/ja00416a009

Reference yield: 70.0%

benzophenone α-chlorophenylacetylhydrazone (79289-08-0) → 1-(diphenylmethylene)-3-oxo-4-phenyl-1,2-diazetidinium inner salt (79289-83-1) + phenylketene (3496-32-0) + diazodiphenylmethane (908093-98-1)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 24h; Title compound not separated from byproducts; Heating;

DOI:10.1021/ja00416a009

Reference yield:

benzophenone α-chlorophenylacetylhydrazone (79289-08-0) → 1-benzhydryl-4-phenyldiazetidin-3-one (21083-13-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / 53percent sodium hydride / tetrahydrofuran / 24 h / Heating

2: 83 percent / sodium borohydride / methanol / 1 h / 0 °C

With sodium tetrahydroborate; sodium hydride; In tetrahydrofuran; methanol;

DOI:10.1021/ja00416a009

upstream raw materials:

benzophenone hydrazone

α-chlorophenylacetyl chloride

Downstream raw materials:

1-(diphenylmethylene)-3-oxo-4-phenyl-1,2-diazetidinium inner salt

phenylketene

diazodiphenylmethane

1-benzhydryl-4-phenyldiazetidin-3-one