Technology Process of 1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene
There total 10 articles about 1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 98 percent / pig liver esterase, (0.1 M phosphate buffer) / 23 °C
2: BH3*(CH3)2S, H2O / tetrahydrofuran / 1 h / 20 °C
4: 92 percent / NaBH4 / methanol; H2O / 5 h / 20 °C
5: 95 percent / Et3N, DMAP / CH2Cl2 / 5 h / 0 - 20 °C
6: 94 percent / powered NaOH / diethyl ether / 5 h / 20 °C
With
dmap; sodium hydroxide; sodium tetrahydroborate; pig liver esterase; dimethylsulfide borane complex; phosphate buffer); water; triethylamine;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0040-4020(01)85099-7
- Guidance literature:
-
Multi-step reaction with 5 steps
1: BH3*(CH3)2S, H2O / tetrahydrofuran / 1 h / 20 °C
3: 92 percent / NaBH4 / methanol; H2O / 5 h / 20 °C
4: 95 percent / Et3N, DMAP / CH2Cl2 / 5 h / 0 - 20 °C
5: 94 percent / powered NaOH / diethyl ether / 5 h / 20 °C
With
dmap; sodium hydroxide; sodium tetrahydroborate; dimethylsulfide borane complex; water; triethylamine;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0040-4020(01)85099-7
