1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene

Base Information

Chemical Name:1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene
CAS No.:116415-56-6
Molecular Formula:C₂₄H₄₀O₃SSi
Molecular Weight:436.731
Hs Code.:

Synonyms:1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene

Suppliers and Price of 1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene

There total 10 articles about 1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 116415-55-5,116500-98-2,116500-99-3,116501-00-9
1-t-butyldimethylsilyloxy (R)-3,9-dimethyl (R,S)-6-phenylsulfonyl 8-decen (R,S)-5-yl acetate

: 116415-56-6
1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene

Guidance literature:: With sodium hydroxide; In diethyl ether; at 20 ℃; for 5h;
DOI:10.1016/S0040-4020(01)85099-7

Reference yield:

: 19013-37-7
dimethyl 3-methylglutarate

: 116415-56-6
1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene

Guidance literature:: Multi-step reaction with 6 steps

1: 98 percent / pig liver esterase, (0.1 M phosphate buffer) / 23 °C

2: BH₃*(CH₃)2S, H₂O / tetrahydrofuran / 1 h / 20 °C

4: 92 percent / NaBH₄ / methanol; H₂O / 5 h / 20 °C

5: 95 percent / Et₃N, DMAP / CH₂Cl₂ / 5 h / 0 - 20 °C

6: 94 percent / powered NaOH / diethyl ether / 5 h / 20 °C

With dmap; sodium hydroxide; sodium tetrahydroborate; pig liver esterase; dimethylsulfide borane complex; phosphate buffer); water; triethylamine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0040-4020(01)85099-7

Reference yield:

: 63473-60-9
(R)-3-methylpentanedioic acid monomethyl ester

: 116415-56-6
1-t-butyldimethylsilyloxy (S)-3,9-dimethyl 6-phenylsulfonyl (E)-5,8-decadiene

Guidance literature:: Multi-step reaction with 5 steps

1: BH₃*(CH₃)2S, H₂O / tetrahydrofuran / 1 h / 20 °C

3: 92 percent / NaBH₄ / methanol; H₂O / 5 h / 20 °C

4: 95 percent / Et₃N, DMAP / CH₂Cl₂ / 5 h / 0 - 20 °C

5: 94 percent / powered NaOH / diethyl ether / 5 h / 20 °C

With dmap; sodium hydroxide; sodium tetrahydroborate; dimethylsulfide borane complex; water; triethylamine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water;
DOI:10.1016/S0040-4020(01)85099-7