(R)-3-Amino-3-(3-fluorophenyl)propanoic acid

Base Information

Chemical Name:(R)-3-Amino-3-(3-fluorophenyl)propanoic acid
CAS No.:723284-81-9
Molecular Formula:C₉H₁₀FNO₂
Molecular Weight:183.182
Hs Code.:2922498590
DSSTox Substance ID:DTXSID10353312
Nikkaji Number:J2.640.873C
Mol file:723284-81-9.mol

Synonyms:723284-81-9;(R)-3-Amino-3-(3-fluorophenyl)propanoic acid;(3R)-3-amino-3-(3-fluorophenyl)propanoic acid;(r)-3-amino-3-(3-fluoro-phenyl)-propionic acid;MFCD04113656;(R)-3-Amino-3-(3-fluorophenyl)-propionic acid;h-d-beta-phe(3-f)-oh;(R)-3-Amino-3-(3-fluorophenyl)propanoicacid;R-3-Amino-3-(3-fluoro-phenyl)-propionic acid;h-phg(3-f)-(c*ch2)oh;SCHEMBL3511663;(R)- -(3-Fluorophenyl)alanine;DTXSID10353312;GZNJUJNKZBHINS-MRVPVSSYSA-N;(r)-beta-(3-fluorophenyl)alanine;H-Phg(3-F)-(C#CH2)OH;(r)-3-(3-fluorophenyl)-beta-alanine;AKOS016844076;DS-4102;AC-25386;CS-0156914;(r)-3-amino-3-(3-fluorophenyl)propionic acid;EN300-1287871;(r)-3-amino-3-(3-fluoro-phenyl)-propanoic acid

Suppliers and Price of (R)-3-Amino-3-(3-fluorophenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

JR MediChem
Benzenepropanoicacid,?-amino-3-fluoro-,(?R)- 96%
25g
$ 4980.00

JR MediChem
Benzenepropanoicacid,?-amino-3-fluoro-,(?R)- 96%
5g
$ 1280.00

Crysdot
(R)-3-Amino-3-(3-fluorophenyl)propanoicacid 95+%
5g
$ 653.00

ChemPep
H-D-β-Phe(3-F)-OH
5g
$ 238.00

ChemPep
H-D-β-Phe(3-F)-OH
25g
$ 714.00

Chemenu
(R)-3-amino-3-(3-fluorophenyl)propanoicacid 95%
5g
$ 617.00

Chemenu
(R)-3-amino-3-(3-fluorophenyl)propanoicacid 95%
1g
$ 201.00

Apolloscientific
(R)-3-Amino-3-(3-fluorophenyl)propionicacid 97%
1g
$ 348.00

Apolloscientific
(R)-3-Amino-3-(3-fluorophenyl)propionicacid 97%
500mg
$ 241.00

Apolloscientific
(R)-3-Amino-3-(3-fluorophenyl)propionicacid 97%
5g
$ 1044.00

Total 31 raw suppliers

Chemical Property of (R)-3-Amino-3-(3-fluorophenyl)propanoic acid

Chemical Property:

Melting Point:217.8-218.4 °C
Boiling Point:305.7±32.0 °C(Predicted)
PKA:3.61±0.10(Predicted)
PSA：63.32000
Density:1.289±0.06 g/cm3(Predicted)
LogP:1.65290
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:-1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:183.06955672
Heavy Atom Count:13
Complexity:187

Purity/Quality:

97% ^*data from raw suppliers

Benzenepropanoicacid,?-amino-3-fluoro-,(?R)- 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)F)C(CC(=O)O)N
Isomeric SMILES:C1=CC(=CC(=C1)F)[C@@H](CC(=O)O)N

Technology Process of (R)-3-Amino-3-(3-fluorophenyl)propanoic acid

There total 28 articles about (R)-3-Amino-3-(3-fluorophenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1393363-73-9,309757-71-9
tert-butyl (S)-3-amino-3-(3'-fluorophenyl)propanoate

: 723284-79-5,723284-81-9
(S)-3-amino-3-(3'-fluorophenyl)propanoic acid

Guidance literature:: tert-butyl (S)-3-amino-3-(3'-fluorophenyl)propanoate; With hydrogenchloride; water; for 6h; Reflux;

With ammonium hydroxide; In water;
DOI:10.1016/j.tetasy.2012.07.001

Reference yield: 45.0%

: n-propyl 3-amino-3-(3-fluorophenyl)propionate

: n-propyl 3-amino-3-(3-fluorophenyl)propionate

: 723284-81-9
3-amino-3-(3-fluorophenyl)propionic acid

Guidance literature:: With potassium dihydrogenphosphate; water; Amano Lipase PS; In cyclohexane; at 30 ℃; for 10h; pH=8.2; Product distribution / selectivity; Resolution of racemate;

Reference yield: 45.0%

: ethyl 3-amino-3-(3-fluorophenyl)propionate

: 723284-81-9
3-amino-3-(3-fluorophenyl)propionic acid

: ethyl 3-amino-3-(3-fluorophenyl)propionate

Guidance literature:: With potassium dihydrogenphosphate; water; Amano Lipase PS; In cyclohexane; at 30 ℃; for 5h; pH=8.2; Product distribution / selectivity; Resolution of racemate;