Technology Process of C25H26BrNO2
There total 7 articles about C25H26BrNO2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C24H26BrNO2; eschenmoser's salt;
With
lithium hexamethyldisilazane;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 2.5h;
Inert atmosphere;
With
3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
at 0 - 23 ℃;
for 0.25h;
enantiospecific reaction;
Inert atmosphere;
DOI:10.1021/ja501142e
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 0 °C / Inert atmosphere
1.2: 0.33 h / Inert atmosphere
2.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 5 h / -78 - 23 °C / Inert atmosphere
2.2: 24 h / 65 °C / Inert atmosphere
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / 23 °C / Inert atmosphere
4.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; 4-methylmorpholine N-oxide / dimethyl sulfoxide / 19 h / 45 °C / Inert atmosphere
5.1: lithium hexamethyldisilazane / tetrahydrofuran / 2.5 h / -78 - 20 °C / Inert atmosphere
5.2: 0.25 h / 0 - 23 °C / Inert atmosphere
With
tetrabutyl ammonium fluoride; sodium hydride; 4-methylmorpholine N-oxide; 9-bora-bicyclo[3.3.1]nonane; lithium hexamethyldisilazane; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; dimethyl sulfoxide; mineral oil;
DOI:10.1021/ja501142e
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 9-bora-bicyclo[3.3.1]nonane / tetrahydrofuran / 5 h / -78 - 23 °C / Inert atmosphere
1.2: 24 h / 65 °C / Inert atmosphere
2.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.33 h / 23 °C / Inert atmosphere
3.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; 4-methylmorpholine N-oxide / dimethyl sulfoxide / 19 h / 45 °C / Inert atmosphere
4.1: lithium hexamethyldisilazane / tetrahydrofuran / 2.5 h / -78 - 20 °C / Inert atmosphere
4.2: 0.25 h / 0 - 23 °C / Inert atmosphere
With
tetrabutyl ammonium fluoride; 4-methylmorpholine N-oxide; 9-bora-bicyclo[3.3.1]nonane; lithium hexamethyldisilazane; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione;
In
tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/ja501142e
