Phe-Tyr methyl ester trifluoroacetate

Base Information

Chemical Name:Phe-Tyr methyl ester trifluoroacetate
CAS No.:70930-22-2
Molecular Formula:C₂HF₃O₂*C₁₉H₂₂N₂O₄
Molecular Weight:456.419
Hs Code.:

Synonyms:Phe-Tyr methyl ester trifluoroacetate

Suppliers and Price of Phe-Tyr methyl ester trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Phe-Tyr methyl ester trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Phe-Tyr methyl ester trifluoroacetate

There total 5 articles about Phe-Tyr methyl ester trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.2%

: 66076-54-8
N-tert-butyloxycarbonyl-L-phenylalanine-L-tyrosine methyl ester

: 76-05-1
trifluoroacetic acid

: 70930-22-2
Phe-Tyr methyl ester trifluoroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1039/d0nj04260a

Reference yield:

: 60-18-4,18875-48-4,25619-78-7,30704-25-7
L-tyrosine

: 70930-22-2
Phe-Tyr methyl ester trifluoroacetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / 12 h / Inert atmosphere; Reflux

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 1 h / 0 °C / Inert atmosphere

2.2: 12 h / 0 - 20 °C / Inert atmosphere; Alkaline conditions

3.1: dichloromethane / 1 h / 20 °C / Inert atmosphere

With thionyl chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/d0nj04260a

Reference yield:

: 3417-91-2
L-tyrosine methyl ester HCl

: 70930-22-2
Phe-Tyr methyl ester trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 1 h / 0 °C / Inert atmosphere

1.2: 12 h / 0 - 20 °C / Inert atmosphere; Alkaline conditions

2.1: dichloromethane / 1 h / 20 °C / Inert atmosphere

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/d0nj04260a