Technology Process of N-benzyl-3,6-di-O-benzyl-L-ido-3,4,5,6-tetrahydroxyazepane
There total 13 articles about N-benzyl-3,6-di-O-benzyl-L-ido-3,4,5,6-tetrahydroxyazepane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
methanol;
at 20 ℃;
for 2h;
DOI:10.1039/b316506j
- Guidance literature:
-
With
toluene-4-sulfonic acid;
palladium on activated charcoal;
In
methanol;
at 64 ℃;
for 5h;
DOI:10.1039/b316506j
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: (Bu3Sn)2O / toluene / 1.5 h / 110 °C
1.2: 53 percent / Bu4NBr / toluene / 2 h / 110 °C
2.1: 53 percent / 4-(dimethylamino)pyridine; pyridine / 0.67 h / 0 - 20 °C
3.1: (1,5-cyclooctadiene)bis(PPh2Me)Ir(I)*PF6 / tetrahydrofuran / 1.5 h / 20 °C
3.2: 60 percent / AcCl / tetrahydrofuran; methanol / 0.5 h / 20 °C
4.1: imidazole / dimethylformamide / 18 h / 85 °C
4.2: 60 percent / 2,6-lutidine / dimethylformamide / 18 h / 65 °C
5.1: 83 percent / NaOMe / methanol / 18 h / 20 °C / pH 12
6.1: 82 percent / aq. NaIO4 / acetonitrile / 6 h / 65 °C
7.1: 59 percent / NaCNBH3; AcOH; 3 Angstroem molecular sieves / methanol / 18 h / -78 - 20 °C
8.1: 93 percent / aq. HCl / methanol / 2 h / 20 °C
With
pyridine; 1H-imidazole; hydrogenchloride; dmap; sodium periodate; 3 A molecular sieve; sodium methylate; sodium cyanoborohydride; acetic acid; bis(tri-n-butyltin)oxide;
(1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate;
In
tetrahydrofuran; methanol; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1039/b316506j
