4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene

Base Information

• Chemical Name: 4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene
• CAS No.: 153936-30-2
• Molecular Formula: C₂₉H₂₄O₄
• Molecular Weight: 436.507
• Mol file: 153936-30-2.mol

Synonyms:4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene

Chemical Property of 4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene

There total 1 articles about 4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.2%

7-methoxoyflavone (22395-22-8) + (4-(benzyloxy)phenyl)magnesium bromide (120186-59-6) → 4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene (153936-30-2)

Guidance literature:

In tetrahydrofuran; diethyl ether; at 70 ℃; for 4h;

Reference yield: 65.9%

4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene (153936-30-2) → 4-(p-benzyloxyphenyl)-7-methoxy-2-phenylchroman

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; for 10h; under 2585.7 Torr;

Reference yield:

4-(p-benzyloxyphenyl)-4-hydroxy-7-methoxy-2-phenyl-4H-chromene (153936-30-2) → 4-(p-hydroxyphenyl)-7-methoxy-2-phenylchroman

Guidance literature:

Multi-step reaction with 2 steps

1: 65.9 percent / H₂ / 10percent Pd/C / tetrahydrofuran / 10 h / 2585.7 Torr

2: 21.2 percent / H₂ / 10percent Pd/C / tetrahydrofuran / 6 h / 3102.9 Torr

With hydrogen; palladium on activated charcoal; In tetrahydrofuran;

upstream raw materials:

7-methoxoyflavone

(4-(benzyloxy)phenyl)magnesium bromide