5-(benzyloxycarbonylamino)isophthalic acid

Base Information

• Chemical Name: 5-(benzyloxycarbonylamino)isophthalic acid
• CAS No.: 153233-30-8
• Molecular Formula: C₁₆H₁₃NO₆
• Molecular Weight: 315.282
• Mol file: 153233-30-8.mol

Synonyms:5-(benzyloxycarbonylamino)isophthalic acid

Chemical Property of 5-(benzyloxycarbonylamino)isophthalic acid

Chemical Property:

Purity/Quality:

99.3% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(benzyloxycarbonylamino)isophthalic acid

There total 1 articles about 5-(benzyloxycarbonylamino)isophthalic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5-aminoisophthalic acid (99-31-0) + benzyl chloroformate (501-53-1,94274-21-2) → 5-(benzyloxycarbonylamino)isophthalic acid (153233-30-8)

Guidance literature:

With sodium hydroxide; for 6h; Ambient temperature;

DOI:10.1021/ja9723951

Reference yield: 99.0%

N-(3-aminopropyl)-N,N'-bis(tert-butoxycarbonyl)propane-1,3-diamine (122248-82-2) + 5-(benzyloxycarbonylamino)isophthalic acid (153233-30-8) → C48H75N7O12

Guidance literature:

With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In N,N-dimethyl-formamide; at 20 ℃; for 21h;

DOI:10.1002/cmdc.201700467

Reference yield: 95.0%

N-(tert-butoxycarbonyl)-1,7-heptanediamine (99733-18-3) + 5-(benzyloxycarbonylamino)isophthalic acid (153233-30-8) → C40H61N5O8

Guidance literature:

With 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1246/bcsj.20090315

upstream raw materials:

5-aminoisophthalic acid

benzyl chloroformate

Downstream raw materials:

(3,5-Bis-chlorocarbonyl-phenyl)-carbamic acid benzyl ester

{[3-Benzyloxycarbonylamino-5-(bis-ethoxycarbonylmethyl-carbamoyl)-benzoyl]-ethoxycarbonylmethyl-amino}-acetic acid ethyl ester

BrH*C₅₆H₆₉N₇O₂₂