ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate

Base Information

Chemical Name:ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate
CAS No.:876161-64-7
Molecular Formula:C₂₀H₂₁ClN₄O₃
Molecular Weight:400.865
Hs Code.:

Synonyms:ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate

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Technology Process of ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate

There total 1 articles about ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 876159-94-3
ethyl (2E)-3-(5-chloro-2-pyrazinyl)acrylate

: 876159-76-1
(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinamine

: 876161-64-7
ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; at 120 ℃; for 3h;

Reference yield:

: 876161-64-7
ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate

: C₁₈H₁₇ClN₄O₃

Guidance literature:: ethyl (2E)-3-(5-{[(3R)-1-(4-chlorobenzoyl)-3-pyrrolidinyl]amino}-2-pyrazinyl)acrylate; With sodium hydroxide; water; In 1,4-dioxane; at 60 ℃; for 2h;

With hydrogenchloride; In 1,4-dioxane; water; pH=7;