3-Fluoro-4'-formyl[1,1'-biphenyl]-2-carbonitrile

Base Information

Chemical Name:3-Fluoro-4'-formyl[1,1'-biphenyl]-2-carbonitrile
CAS No.:718628-28-5
Molecular Formula:C₁₃H₈ClFO
Molecular Weight:234.657
Hs Code.:
DSSTox Substance ID:DTXSID20699112
Wikidata:Q82629859
Mol file:718628-28-5.mol

Synonyms:DTXSID20699112;BS-24393;4-(2-CYANO-3-FLUOROPHENYL)BENZALDEHYDE;3-Fluoro-4'-formyl[1,1'-biphenyl]-2-carbonitrile

Suppliers and Price of 3-Fluoro-4'-formyl[1,1'-biphenyl]-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(3-Chloro-4-fluorophenyl)benzaldehyde
250mg
$ 75.00

Crysdot
4-(3-Chloro-4-fluorophenyl)benzaldehyde 95+%
5g
$ 339.00

Crysdot
4-(3-Chloro-4-fluorophenyl)benzaldehyde 95+%
10g
$ 564.00

AK Scientific
4-(3-Chloro-4-fluorophenyl)benzaldehyde
5g
$ 531.00

Total 6 raw suppliers

Chemical Property of 3-Fluoro-4'-formyl[1,1'-biphenyl]-2-carbonitrile

Chemical Property:

PSA：40.86000
LogP:3.17688
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:225.058992041
Heavy Atom Count:17
Complexity:313

Purity/Quality:

99%+ ^*data from raw suppliers

4-(3-Chloro-4-fluorophenyl)benzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C(=C1)F)C#N)C2=CC=C(C=C2)C=O

Technology Process of 3-Fluoro-4'-formyl[1,1'-biphenyl]-2-carbonitrile

There total 3 articles about 3-Fluoro-4'-formyl[1,1'-biphenyl]-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 718628-28-5
3'-chloro-4'-fluoro[1,1'-biphenyl]-4-carbaldehyde

Guidance literature:

Reference yield: 75.0%

: 1122-91-4
4-bromo-benzaldehyde

: 137504-86-0
3-fluoro-4-chlorophenylboronic acid

: 718628-28-5
3'-chloro-4'-fluoro[1,1'-biphenyl]-4-carbaldehyde

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,2-dimethoxyethane; ethanol; water; at 65 ℃; for 1h;
DOI:10.1016/j.ejmech.2016.12.024

Reference yield:

: 156150-67-3
3-chloro-4-fluoroiodobenzene

: 1122-91-4
4-bromo-benzaldehyde

: 718628-28-5
3'-chloro-4'-fluoro[1,1'-biphenyl]-4-carbaldehyde

Guidance literature:: 3-chloro-4-fluoroiodobenzene; With copper; zinc; In N,N-dimethyl-formamide; at 100 ℃; for 0.0333333h;

4-bromo-benzaldehyde; With bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 120 ℃; for 0.0833333h; Further stages.;
DOI:10.1016/j.tetlet.2004.03.118