Technology Process of [1-(4-bromobenzenesulfonyl)-6-methoxy-1H-indol-3-yl]-(3,4,5-trimethoxyphenyl)methanone
There total 1 articles about [1-(4-bromobenzenesulfonyl)-6-methoxy-1H-indol-3-yl]-(3,4,5-trimethoxyphenyl)methanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
dichloromethane;
for 3h;
- Guidance literature:
-
With
palladium diacetate; potassium carbonate; triethylamine; triphenylphosphine;
In
N,N-dimethyl-formamide;
at 100 ℃;
for 5h;
Inert atmosphere;
DOI:10.1016/j.ejmech.2016.11.033
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triphenylphosphine; palladium diacetate; potassium carbonate; triethylamine / N,N-dimethyl-formamide / 5 h / 100 °C / Inert atmosphere
2: trifluoroacetic acid / 16 h / 20 °C / Inert atmosphere
3: benzotriazol-1-ol; 4-methyl-morpholine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 2 h / 20 °C / Inert atmosphere
With
4-methyl-morpholine; palladium diacetate; potassium carbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; triphenylphosphine; trifluoroacetic acid;
In
N,N-dimethyl-formamide;
1: |Heck Reaction;
DOI:10.1016/j.ejmech.2016.11.033
