tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate

Base Information

• Chemical Name: tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate
• CAS No.: 1354828-51-5
• Molecular Formula: C₂₁H₂₇N₃O₃
• Molecular Weight: 369.464
• Mol file: 1354828-51-5.mol

Synonyms:tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate

Chemical Property of tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate

There total 6 articles about tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

N-ethyl-p-tyramine (119045-87-3) + tert-butyl 2-(4-nitrophenyl)diazenecarboxylate (92722-14-0) → tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate (1354828-51-5)

Guidance literature:

N-ethyl-p-tyramine; With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

tert-butyl 2-(4-nitrophenyl)diazenecarboxylate; In N,N-dimethyl-formamide; Inert atmosphere;

DOI:10.1021/jo202406k

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate (1354828-51-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: acetonitrile / 20 °C / Inert atmosphere

2.1: manganese(IV) oxide / dichloromethane / 20 °C / Inert atmosphere

3.1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

3.2: Inert atmosphere

With manganese(IV) oxide; caesium carbonate; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1021/jo202406k

Reference yield:

tert-butyl 2-(4-cyanophenyl)diazene-1-carboxylate (1354828-66-2) → tert-butyl 2-(4-(4-(2-(ethylamino)ethyl)phenoxy)phenyl)azocarboxylate (1354828-51-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: manganese(IV) oxide / dichloromethane / Inert atmosphere

2.1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C / Inert atmosphere

2.2: Inert atmosphere

With manganese(IV) oxide; caesium carbonate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo202406k

upstream raw materials:

tert-butyl 2-(4-cyanophenyl)diazene-1-carboxylate

4-hydrazinobenzonitrile

di-tert-butyl dicarbonate

N-ethyl-p-tyramine