(1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl)

Base Information

• Chemical Name: (1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl)
• CAS No.: 1043927-41-8
• Molecular Formula: C₂₁H₃₇F₃NiP₂
• Molecular Weight: 467.158
• Mol file: 1043927-41-8.mol

Synonyms:(1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl)

Chemical Property of (1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl)

There total 2 articles about (1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

(1,2-bis(diisopropylphosphino)ethane)Ni(Ph)Br (1043927-33-8) + (trifluoromethyl)trimethylsilane (81290-20-2) → (1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl) (1043927-41-8)

Guidance literature:

With cesium fluoride; In tetrahydrofuran; under N2; mixt. of Ni complex, CsF, CF3SiMe3 and THF stirred at room temp. for 14 h; filtered through alumina pad; filtrate concd. under high vac.; solid washed with toluene and pentane; dried under vac.; elem. anal.;

DOI:10.1021/om800300k

Reference yield:

bromobenzene (108-86-1,52753-63-6) + 1,1'-(1,2-ethanediyl)bis[1,1-bis(1-methylethyl)phosphine] (87532-69-2) → (1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl) (1043927-41-8)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene

2: cesium fluoride / tetrahydrofuran

With cesium fluoride; In tetrahydrofuran; toluene;

DOI:10.1021/om800300k

Reference yield: 22.0%

(1,2-bis(diisopropylphosphino)ethane)Ni(Ph)(trifluoromethyl) (1043927-41-8) + water (7732-18-5) → α,α,α-trifluorotoluene (98-08-8) + nickel(II) hydroxide

Guidance literature:

In toluene; byproducts: PhCOF; under N2; Ni complex in toluene in presence of H2O heated at 80°Cfor 5 h;

DOI:10.1021/om800300k

upstream raw materials:

(1,2-bis(diisopropylphosphino)ethane)Ni(Ph)Br

(trifluoromethyl)trimethylsilane

bromobenzene

1,1'-(1,2-ethanediyl)bis[1,1-bis(1-methylethyl)phosphine]

Downstream raw materials:

α,α,α-trifluorotoluene

(1,2-bis(diisopropylphosphino)ethane)Ni(trifluoromethyl)2

nickel