6-chloro-7-methoxy-N-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide

Base Information

• Chemical Name: 6-chloro-7-methoxy-N-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide
• CAS No.: 1246674-62-3
• Molecular Formula: C₁₇H₁₇ClNO*I
• Molecular Weight: 413.686
• Mol file: 1246674-62-3.mol

Synonyms:6-chloro-7-methoxy-N-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide

Chemical Property of 6-chloro-7-methoxy-N-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 6-chloro-7-methoxy-N-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide

There total 1 articles about 6-chloro-7-methoxy-N-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

6-chloro-7-methoxy-1-phenyl-3,4-dihydroisoquinoline (115514-68-6) + methyl iodide (74-88-4) → 6-chloro-7-methoxy-N-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide (1246674-62-3)

Guidance literature:

In acetone; for 1h; Reflux;

DOI:10.1002/ejoc.201000512

Reference yield: 98.0%

6-chloro-7-methoxy-N-methyl-1-phenyl-3,4-dihydroisoquinolinium iodide (1246674-62-3) → 1-phenyl-6-chloro-7-methoxy-N-methyl-1,2,3,4-tetrahydroisoquinoline (115514-70-0)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 2.16667h;

DOI:10.1002/ejoc.201000512

upstream raw materials:

6-chloro-7-methoxy-1-phenyl-3,4-dihydroisoquinoline

methyl iodide

Downstream raw materials:

1-phenyl-6-chloro-7-methoxy-N-methyl-1,2,3,4-tetrahydroisoquinoline