(3R)-3-(Hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one

Base Information

Chemical Name:(3R)-3-(Hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one
CAS No.:714569-16-1
Molecular Formula:C9H10 N2 O2
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID50566368
Wikidata:Q82451954
Mol file:714569-16-1.mol

Synonyms:714569-16-1;(3R)-3-(HYDROXYMETHYL)-3,4-DIHYDROQUINOXALIN-2(1H)-ONE;SCHEMBL5579750;DTXSID50566368;YHYHTJWKQDOTLD-MRVPVSSYSA-N;2(1H)-Quinoxalinone,3,4-dihydro-3-(hydroxymethyl)-,(3R)-(9CI)

Suppliers and Price of (3R)-3-(Hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3R)-3-(Hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one

Chemical Property:

PSA：61.36000
LogP:0.68750
XLogP3:0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:178.074227566
Heavy Atom Count:13
Complexity:208

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(C(=O)N2)CO
Isomeric SMILES:C1=CC=C2C(=C1)N[C@@H](C(=O)N2)CO

Technology Process of (3R)-3-(Hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one

There total 2 articles about (3R)-3-(Hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 714569-16-1
(3R)-3-(hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one

Guidance literature:

Reference yield:

: 714569-12-7
N-(2-nitrophenyl)-O-benzyl-D-serine methyl ester

: 714569-16-1
(3R)-3-(hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; under 2844.39 Torr; Parr Hydrogenator;

Reference yield:

: 714569-16-1
(3R)-3-(hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one

: 7035-02-1
o-Methoxybenzyl chloride

: (3R)-3-{[(2-methoxybenzyl)oxy]methyl}-3,4-dihydro-quinoxalin-2(1H)-one

Guidance literature:: (3R)-3-(hydroxymethyl)-3,4-dihydroquinoxalin-2(1H)-one; With sodium hydride; In DMF (N,N-dimethyl-formamide); at 0 ℃; for 0.25h;

o-Methoxybenzyl chloride; In DMF (N,N-dimethyl-formamide); at 20 ℃;