2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside

Base Information

• Chemical Name: 2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside
• CAS No.: 1430098-31-9
• Molecular Formula: C₄₆H₄₃IO₁₀
• Molecular Weight: 882.746
• Mol file: 1430098-31-9.mol

Synonyms:2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside

Chemical Property of 2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside

There total 2 articles about 2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

2,3,4,6-tetra-O-benzoylglucosyl bromide (14218-11-2) + 2-tert-butyl-4-ethyl-6-iodophenol (330935-93-8) → 2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside (1430098-31-9)

Guidance literature:

With tetrabutylammomium bromide; sodium hydroxide; In chloroform; water; at 20 ℃; for 2.5h;

DOI:10.1002/ejoc.201201376

Reference yield:

6-di-t-butyl-4-ethylphenol (96-70-8) → 2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside (1430098-31-9)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium iodide; sodium hypochlorite; sodium hydroxide / methanol / 1 h / 0 - 3 °C / Inert atmosphere

2: sodium hydroxide; tetrabutylammomium bromide / chloroform; water / 2.5 h / 20 °C

With sodium hypochlorite; tetrabutylammomium bromide; sodium iodide; sodium hydroxide; In methanol; chloroform; water;

DOI:10.1002/ejoc.201201376

Reference yield: 59.0%

2-tert-butyl-4-ethyl-6-iodophenyl 2,3,4,6-tetra-O-benzoyl-β-D-glucopyranoside (1430098-31-9) → 2-tert-butyl-4-ethyl-6-iodophenyl β-D-glucopyranoside (1430098-32-0)

Guidance literature:

With water; triethylamine; In methanol; at 20 ℃; for 41h; Reflux;

DOI:10.1002/ejoc.201201376

upstream raw materials:

6-di-t-butyl-4-ethylphenol

2,3,4,6-tetra-O-benzoylglucosyl bromide

2-tert-butyl-4-ethyl-6-iodophenol

Downstream raw materials:

2-tert-butyl-4-ethyl-6-iodophenyl β-D-glucopyranoside