1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose

Base Information

• Chemical Name: 1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose
• CAS No.: 1025482-97-6
• Molecular Formula: C₃₅H₂₇F₃O₁₂S
• Molecular Weight: 728.653
• Mol file: 1025482-97-6.mol

Synonyms:1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose

Chemical Property of 1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose

There total 5 articles about 1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

trifluoromethylsulfonic anhydride (358-23-6) + 1,2,3,6-tetra-O-benzoyl-α-D-galactopyranose (114718-46-6) → 1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose (1025482-97-6)

Guidance literature:

With pyridine; In dichloromethane; at -20 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.bmc.2018.02.031

Reference yield:

1,2,3,6-tetra-O-benzoyl-D-galactopyranose (86420-80-6) + trifluoromethylsulfonic anhydride (358-23-6) → 1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose (1025482-97-6)

Guidance literature:

With pyridine; In dichloromethane; at -10 ℃; for 1h;

DOI:10.1021/ja068602r

Reference yield:

D-Galactose (10257-28-0) → 1,2,3,6-tetra-O-benzoyl-4-O-trifluoromethylsulfonyl-D-galactopyranose (1025482-97-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / pyridine / -40 - 1 °C

2: pyridine / CH₂Cl₂ / 1 h / -10 °C

With pyridine; In dichloromethane;

DOI:10.1021/ja068602r

upstream raw materials:

1,2,3,6-tetra-O-benzoyl-D-galactopyranose

trifluoromethylsulfonic anhydride

D-Galactose

benzoyl chloride

Downstream raw materials:

4-azido-4-deoxy-1,2,3,6-tetra-O-benzoyl-D-glucopyranose