6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

Base Information

Chemical Name:6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile
CAS No.:1103593-93-6
Molecular Formula:C₂₀H₁₄N₆O₂
Molecular Weight:370.37
Hs Code.:
DSSTox Substance ID:DTXSID20705085
Nikkaji Number:J2.659.839G
Wikidata:Q82637768

Synonyms:6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile;DTXSID20705085;1103593-93-6;1-Phenyl-3-methyl-4-(3-nitrophenyl)-6-amino-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

Suppliers and Price of 6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:370.11782371
Heavy Atom Count:28
Complexity:624

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NN(C2=C1C(=C(C(=N2)N)C#N)C3=CC(=CC=C3)[N+](=O)[O-])C4=CC=CC=C4

Technology Process of 6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

There total 3 articles about 6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1131-18-6
1-Phenyl-3-methyl-5-aminopyrazole

: 93690-11-0
2-cyano-3-(3-nitrophenyl)thioacrylamide

: 1103593-93-6
6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

Guidance literature:: With 1-butyl-3-methylimidazolium Tetrafluoroborate; at 80 ℃; for 5h;
DOI:10.3987/COM-08-11455

Reference yield: 87.0%

: 1131-18-6
1-Phenyl-3-methyl-5-aminopyrazole

: 99-61-6
3-nitro-benzaldehyde

: 109-77-3
malononitrile

: 1103593-93-6
6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

Guidance literature:: at 80 ℃; for 12h; Ionic liquid;
DOI:10.1071/CH08290

Reference yield: 85.0%

: 1131-18-6
1-Phenyl-3-methyl-5-aminopyrazole

: 7357-70-2
Cyanothioacetamide

: 99-61-6
3-nitro-benzaldehyde

: 1103593-93-6
6-amino-3-methyl-4-(3-nitrophenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

Guidance literature:: With piperidine; In ethanol; at 80 ℃; for 0.166667h; chemoselective reaction; Microwave irradiation;
DOI:10.1002/hc.20497