(S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine

Base Information

Chemical Name:(S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine
CAS No.:386253-26-5
Molecular Formula:C₂₇H₃₂N₂O
Molecular Weight:400.564
Hs Code.:

Synonyms:(S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine

Suppliers and Price of (S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine

There total 5 articles about (S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Trifluoro-methanesulfonate1-{[(E)-(S)-1-benzyloxymethyl-2-methyl-propylimino]-phenyl-methyl}-pyridinium;

: 6524-17-0,29283-76-9,6386-72-7
(Z)-1-propenyllithium

: 386253-26-5
(S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine

Guidance literature:: (Z)-1-propenyllithium; With magnesium bromide ethyl etherate; In diethyl ether; at -30 - 20 ℃;

Trifluoro-methanesulfonate1-{[(E)-(S)-1-benzyloxymethyl-2-methyl-propylimino]-phenyl-methyl}-pyridinium;; In diethyl ether; dichloromethane; at -78 - -30 ℃; for 23h; Further stages.;
DOI:10.1021/ja017136x

Reference yield:

: 2026-48-4,473-75-6
(S)-valinol

: 386253-26-5
(S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 84 percent / triethylamine / CH₂Cl₂ / 1.5 h / -10 °C

2.1: NaH / tetrahydrofuran / 2 h / 0 °C

2.2: 97 percent / tetrahydrofuran / 25 °C

3.1: CH₂Cl₂ / 20 h / -40 - 0 °C

4.1: magnesium bromide diethyl etherate / diethyl ether / -30 - 20 °C

4.2: 122.5 mg / CH₂Cl₂; diethyl ether / 23 h / -78 - -30 °C

With sodium hydride; magnesium bromide ethyl etherate; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/ja017136x

Reference yield:

: 98-88-4
benzoyl chloride

: 386253-26-5
(S)-1-(benzyloxy)-3-methyl-N-(phenyl((R)-2-((Z)-prop-1-enyl)pyridin-1(2H)-yl)methylene)butan-2-amine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 84 percent / triethylamine / CH₂Cl₂ / 1.5 h / -10 °C

2.1: NaH / tetrahydrofuran / 2 h / 0 °C

2.2: 97 percent / tetrahydrofuran / 25 °C

3.1: CH₂Cl₂ / 20 h / -40 - 0 °C

4.1: magnesium bromide diethyl etherate / diethyl ether / -30 - 20 °C

4.2: 122.5 mg / CH₂Cl₂; diethyl ether / 23 h / -78 - -30 °C

With sodium hydride; magnesium bromide ethyl etherate; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/ja017136x