(3R,4S)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione

Base Information

Chemical Name:(3R,4S)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione
CAS No.:75112-74-2
Molecular Formula:C₁₁H₁₁NO₄
Molecular Weight:221.213
Hs Code.:
DSSTox Substance ID:DTXSID50352586
Wikidata:Q82129821
Mol file:75112-74-2.mol

Synonyms:75112-74-2;(3R,4S)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione;(3R,4S)-1-Benzyl-3,4-dihydroxy-2,5-pyrrolidinedione;(3S,4R)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione;2,5-Pyrrolidinedione,3,4-dihydroxy-1-(phenylmethyl)-, (3R,4S)-rel-;SCHEMBL14189454;DTXSID50352586;A838326;(3S,4R)-1-benzyl-3,4-dihydroxy-pyrrolidine-2,5-dione

Suppliers and Price of (3R,4S)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(3R,4S)-1-BENZYL-3,4-DIHYDROXY-2,5-PYRROLIDINEDIONE 95.00%
100MG
$ 297.15

Total 4 raw suppliers

Chemical Property of (3R,4S)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione

Chemical Property:

PSA：77.84000
LogP:-0.78490
XLogP3:-0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:221.06880783
Heavy Atom Count:16
Complexity:278

Purity/Quality:

97% ^*data from raw suppliers

(3R,4S)-1-BENZYL-3,4-DIHYDROXY-2,5-PYRROLIDINEDIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CN2C(=O)C(C(C2=O)O)O
Isomeric SMILES:C1=CC=C(C=C1)CN2C(=O)[C@@H]([C@@H](C2=O)O)O

Technology Process of (3R,4S)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione

There total 2 articles about (3R,4S)-1-benzyl-3,4-dihydroxypyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133-37-9,138508-61-9
DL-tartaric acid

: 100-46-9
benzylamine

: 19728-93-9,75112-73-1,75112-74-2,75172-31-5
(+/-)-1-benzyl-3r,4t-dihydroxy-pyrrolidine-2,5-dione

Guidance literature:: With 4 A molecular sieve; In xylene; for 19h; Heating;
DOI:10.1002/chem.200304718

Reference yield:

: 19728-93-9,75112-73-1,75112-74-2,75172-31-5
(+/-)-1-benzyl-3r,4t-dihydroxy-pyrrolidine-2,5-dione

Guidance literature:: With acid;

Reference yield:

: 19728-93-9,75112-73-1,75112-74-2,75172-31-5
(+/-)-1-benzyl-3r,4t-dihydroxy-pyrrolidine-2,5-dione

: N-benzyl-2,3-O-di-tert-butyldimethylsilyl-1,4-dideoxy-1,4-iminothreitol

Guidance literature:: Multi-step reaction with 2 steps

1.1: 11.4 g / imidazole / dimethylformamide / 21 h

2.1: BH₃*Me₂S / tetrahydrofuran / 30 h / 20 °C

2.2: 100 percent / methanol / 20 h / 40 °C

With 1H-imidazole; dimethylsulfide borane complex; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1002/chem.200304718