5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride

Base Information

Chemical Name:5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride
CAS No.:1445869-18-0
Molecular Formula:C₁₉H₂₀FN₅O₅*ClH
Molecular Weight:453.858
Hs Code.:

Synonyms:5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride

Suppliers and Price of 5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride

There total 9 articles about 5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1445869-10-2
5-[1-(2-fluoro-4-[(5-nitro-2-furyl)methyl]aminophenyl)-4-piperidyl]-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one

: 1445869-18-0
5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride

Guidance literature:: With hydrogenchloride; In methanol; at 0 ℃; for 1h;

Reference yield:

: 2971-79-1
isonipecotic acid methyl ester

: 1445869-18-0
5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride

Guidance literature:: Multi-step reaction with 8 steps

1: potassium carbonate / N,N-dimethyl-formamide / 10 h / 80 °C

2: hydrazine hydrate / ethanol / 12 h / Reflux

3: pyridine / 2.5 h / 85 °C / Reflux

4: potassium carbonate / N,N-dimethyl-formamide / 10 h / 0 °C

5: tin(II) chloride dihdyrate / methanol / 4 h / 65 °C / Reflux

6: acetic acid / methanol / 10 h / 0 °C

7: acetic acid; sodium cyanoborohydride / methanol / 12 h / 0 °C

8: hydrogenchloride / methanol / 1 h / 0 °C

With pyridine; hydrogenchloride; tin(II) chloride dihdyrate; sodium cyanoborohydride; potassium carbonate; hydrazine hydrate; acetic acid; In methanol; ethanol; N,N-dimethyl-formamide;

Reference yield:

: 369-34-6
3,4-difluoronitrobenzene

: 1445869-18-0
5-(1-(2-fluoro-4-(1-((5-nitro-2-furyl)methyl)ammonio)phenyl)-4-piperidyl)-3-methyl-2,3-dihydro-1,3,4-oxadiazol-2-one chloride

Guidance literature:: Multi-step reaction with 8 steps

1: potassium carbonate / N,N-dimethyl-formamide / 10 h / 80 °C

2: hydrazine hydrate / ethanol / 12 h / Reflux

3: pyridine / 2.5 h / 85 °C / Reflux

4: potassium carbonate / N,N-dimethyl-formamide / 10 h / 0 °C

5: tin(II) chloride dihdyrate / methanol / 4 h / 65 °C / Reflux

6: acetic acid / methanol / 10 h / 0 °C

7: acetic acid; sodium cyanoborohydride / methanol / 12 h / 0 °C

8: hydrogenchloride / methanol / 1 h / 0 °C

With pyridine; hydrogenchloride; tin(II) chloride dihdyrate; sodium cyanoborohydride; potassium carbonate; hydrazine hydrate; acetic acid; In methanol; ethanol; N,N-dimethyl-formamide;