Tert-butyl 2-(aminooxy)ethylcarbamate

Base Information

• Chemical Name: Tert-butyl 2-(aminooxy)ethylcarbamate
• CAS No.: 75051-55-7
• Molecular Formula: C7H16 N2 O3
• Molecular Weight: 176.216
• European Community (EC) Number: 852-420-6
• DSSTox Substance ID: DTXSID601237733
• Mol file: 75051-55-7.mol

Synonyms:75051-55-7;TERT-BUTYL 2-(AMINOOXY)ETHYLCARBAMATE;tert-butyl N-[2-(aminooxy)ethyl]carbamate;tert-Butyl (2-(aminooxy)ethyl)carbamate;tert-butyl [2-(aminooxy)ethyl]carbamate;TERT-BUTYL N-(2-AMINOOXYETHYL)CARBAMATE;MFCD11934722;CARBAMIC ACID, [2-(AMINOOXY)ETHYL]-, 1,1-DIMETHYLETHYL ESTER (9CI);CARBAMIC ACID, [2-(AMINOOXY)ETHYL]-, 1,1-DIMETHYLETHYL ESTER;tert-Butyl(2-(aminooxy)ethyl)carbamate;tert-butyl[2-(aminooxy)ethyl]carbamate;SCHEMBL1526786;2-(Aminooxy)-N-Boc-ethanamine;JRLJOAREDJOYLW-UHFFFAOYSA-N;DTXSID601237733;tert-butyl N-aminooxyethylcarbamate;AMY30642;AKOS016354866;MB11412;NS-01474;SY099635;CS-0047972;(2-aminooxv-ethyl)-carbamic acid t-butyl ester;(2-aminooxy-ethyl)-carbamic acid t-butyl ester;EN300-1168250;1,1-Dimethylethyl N-[2-(aminooxy)ethyl]carbamate;o-[2-(tert-butoxycarbonylamino)ethyl]hydroxylamine;F1913-0354;Carbamic acid,[2-(aminooxy)ethyl]-,1,1-dimethylethyl ester(9ci)

Chemical Property of Tert-butyl 2-(aminooxy)ethylcarbamate

Chemical Property:

• Boiling Point: 303.0±25.0 °C(Predicted)
• PKA: 12.57±0.46(Predicted)
• PSA: 73.58000
• Density: 1.058±0.06 g/cm3(Predicted)
• LogP: 1.49260
• XLogP3: 0
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 176.11609238
• Heavy Atom Count: 12
• Complexity: 142

Purity/Quality:

99% ^*data from raw suppliers

tert-butyl2-(aminooxy)ethylcarbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NCCON

Technology Process of Tert-butyl 2-(aminooxy)ethylcarbamate

There total 6 articles about Tert-butyl 2-(aminooxy)ethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

[2-(1,3-dioxo-1,3-dihydroisoindol-2-yloxy)-ethyl]carbamic acid tert-butyl ester (87276-51-5) + methylhydrazine (60-34-4) → (2-aminoxyethyl)carbamic acid tert-butyl ester (75051-55-7)

Guidance literature:

In dichloromethane; at 20 ℃; for 72h;

Reference yield: 99.0%

[2-(1,3-dioxo-1,3-dihydroisoindol-2-yloxy)-ethyl]carbamic acid tert-butyl ester (87276-51-5) → (2-aminoxyethyl)carbamic acid tert-butyl ester (75051-55-7)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 2h;

Reference yield: 58.0%

→ (2-aminoxyethyl)carbamic acid tert-butyl ester (75051-55-7)

Guidance literature:

upstream raw materials:

[2-(1,3-dioxo-1,3-dihydroisoindol-2-yloxy)-ethyl]carbamic acid tert-butyl ester

methylhydrazine

di-tert-butyl dicarbonate

2-(N-tert-butoxycarbonylamino)ethanol

Downstream raw materials:

{2-[({[(2S,5R)-6-benzyloxy-7-oxo-1,6-diazabicyclo[3.2.1]oct-2-yl]carbonyl}amino)oxy]ethyl}carbamic acid tert-butyl ester

N-(2-aminoethoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide