Technology Process of N2-allyl-N4-benzyl-6,7-diphenyl-2,4-pteridinediamine
There total 4 articles about N2-allyl-N4-benzyl-6,7-diphenyl-2,4-pteridinediamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-(allylamino)-6,7-diphenyl-4(3H)-pteridinone;
With
(benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
acetonitrile;
at 20 ℃;
for 0.166667h;
benzylamine;
In
acetonitrile;
at 20 ℃;
for 48h;
DOI:10.1016/j.tet.2011.03.011
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 3-chloro-benzenecarboperoxoic acid / N,N-dimethyl-formamide / 3 h / 20 °C / Inert atmosphere
2.1: 1 h / 110 °C / Microwave irradiation
3.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 0.17 h / 20 °C
3.2: 48 h / 20 °C
With
(benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid;
In
N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.tet.2011.03.011
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1 h / 110 °C / Microwave irradiation
2.1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 0.17 h / 20 °C
2.2: 48 h / 20 °C
With
(benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
acetonitrile;
DOI:10.1016/j.tet.2011.03.011
