2-(4-bromo-2-fluorophenyl)-1H-benzimidazole

Base Information

Chemical Name:2-(4-bromo-2-fluorophenyl)-1H-benzimidazole
CAS No.:883230-60-2
Molecular Formula:C₁₃H₈BrFN₂
Molecular Weight:291.122
Hs Code.:
DSSTox Substance ID:DTXSID401260015

Synonyms:2-(4-bromo-2-fluorophenyl)-1H-benzimidazole;SCHEMBL2898110;QUCCGSGXTTYMIL-UHFFFAOYSA-N;DTXSID401260015;AKOS008956974;2-(4-Bromo-2-fluoro-phenyl)-1H-benzimidazole;883230-60-2

Suppliers and Price of 2-(4-bromo-2-fluorophenyl)-1H-benzimidazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-bromo-2-fluorophenyl)-1H-benzimidazole

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:289.98549
Heavy Atom Count:17
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)NC(=N2)C3=C(C=C(C=C3)Br)F

Technology Process of 2-(4-bromo-2-fluorophenyl)-1H-benzimidazole

There total 3 articles about 2-(4-bromo-2-fluorophenyl)-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 4403-69-4
2-amino-1-benzylamine

: 57848-46-1
4-bromo-2-fluorobenzaldehyde

: 883230-60-2
2-(2-fluoro-4-bromophenyl)-1H-benzo[d]imidazole

Guidance literature:: With [bis(acetoxy)iodo]benzene; iodine; In dichloromethane; at 20 ℃; for 1h; chemoselective reaction;
DOI:10.1016/j.tetlet.2017.01.099

Reference yield: 85.0%

: 28144-70-9,88-68-6
anthranilic acid amide

: 57848-46-1
4-bromo-2-fluorobenzaldehyde

: 883230-60-2
2-(2-fluoro-4-bromophenyl)-1H-benzo[d]imidazole

Guidance literature:: With tert.-butylhydroperoxide; iodine; In water; acetonitrile; at 20 ℃; for 2h;
DOI:10.1016/j.tetlet.2018.05.028

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 57848-46-1
4-bromo-2-fluorobenzaldehyde

: 883230-60-2
2-(2-fluoro-4-bromophenyl)-1H-benzo[d]imidazole

Guidance literature:: 4-bromo-2-fluorobenzaldehyde; With sodium hydrogensulfite; In ethanol; water; at 30 ℃; for 1h;

1,2-diamino-benzene; In ethanol; water; for 4h; Heating / reflux;