ethyl-4- 4-oxo-butane carboxylic acid ester

Base Information

• Chemical Name: ethyl-4- 4-oxo-butane carboxylic acid ester
• CAS No.: 154195-24-1
• Molecular Formula: C₁₆H₂₀N₂O₃
• Molecular Weight: 288.346
• Mol file: 154195-24-1.mol

Synonyms:ethyl-4- 4-oxo-butane carboxylic acid ester

Chemical Property of ethyl-4- 4-oxo-butane carboxylic acid ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl-4- 4-oxo-butane carboxylic acid ester

There total 3 articles about ethyl-4- 4-oxo-butane carboxylic acid ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(benzylamino)propionitrile (706-03-6) → ethyl-4- 4-oxo-butane carboxylic acid ester (154195-24-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 84.6 percent / Na₂CO₃ / acetonitrile / 4 h / Heating

2: thionyl chloride / 3 h / Ambient temperature

3: 10 h / Ambient temperature

With thionyl chloride; sodium carbonate; In acetonitrile;

DOI:10.1002/prac.19943360120

Reference yield:

4--4-oxo-butane carboxylic acid (154195-23-0) → ethyl-4- 4-oxo-butane carboxylic acid ester (154195-24-1)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / 3 h / Ambient temperature

2: 10 h / Ambient temperature

With thionyl chloride;

DOI:10.1002/prac.19943360120

Reference yield:

ethanol (64-17-5) + 3-[Benzyl-(2-cyano-ethyl)-carbamoyl]-propionyl chloride → ethyl-4- 4-oxo-butane carboxylic acid ester (154195-24-1)

Guidance literature:

for 10h; Ambient temperature;

DOI:10.1002/prac.19943360120

upstream raw materials:

ethanol

3-(benzylamino)propionitrile

4--4-oxo-butane carboxylic acid