(1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

Base Information

Chemical Name:(1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine
CAS No.:1418754-31-0
Molecular Formula:C₁₇H₂₆N₄O₂
Molecular Weight:318.419
Hs Code.:

(1R,2R)-N<sub>1</sub>-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

Synonyms:(1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

Suppliers and Price of (1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

There total 6 articles about (1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 144872-34-4
1-(4-nitrophenyl)piperidin-3-one

: 20439-47-8
(1R,2R)-1,2-diaminocyclohexane

: 1418754-31-0
(1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

Guidance literature:: 1-(4-nitrophenyl)piperidin-3-one; (1R,2R)-1,2-diaminocyclohexane; With acetic acid; sodium sulfate; In dichloromethane; at 20 ℃; for 1.01667h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In dichloromethane; at 20 ℃; for 4h;

Reference yield:

: 1418755-26-6
(1R,2R)-N₁-(1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

: 1418754-31-0
(1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

Guidance literature:: With trifluoroacetic acid; In methanol; water; Resolution of racemate;

Reference yield:

: 99841-68-6
1-(4-nitrophenyl)piperidin-3-ol

: 1418754-31-0
(1R,2R)-N₁-((S)-1-(4-nitrophenyl)piperidin-3-yl)cyclohexane-1,2-diamine

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 0 °C

1.2: 2 h / 0 - 20 °C

2.1: sodium sulfate; acetic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere

2.2: 4 h / 20 °C

3.1: trifluoroacetic acid / methanol; water / Resolution of racemate

With acetic acid; sodium sulfate; triethylamine; trifluoroacetic acid; In methanol; dichloromethane; water;